1254965-36-0

Basic information

• Product Name: rac-5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid (tetrahydro-furan-3-yl)-amide
• Synonyms: rac-5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid (tetrahydro-furan-3-yl)-amide
• CAS NO: 1254965-36-0
• Molecular Weight: 416.409
• Mol File: 1254965-36-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: rac-5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid (tetrahydro-furan-3-yl)-amide(CAS DataBase Reference)
• NIST Chemistry Reference: rac-5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid (tetrahydro-furan-3-yl)-amide(1254965-36-0)
• EPA Substance Registry System: rac-5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid (tetrahydro-furan-3-yl)-amide(1254965-36-0)

Safety Data

• Hazardous Substances Data: 1254965-36-0(Hazardous Substances Data)

Upstream product

• 88675-24-5 3-aminotetrahydrofuran 
• 1254966-33-0 5-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid 
• 954230-39-8 3-(4-fluoro-phenyl)-5-methyl-isoxazole-4-carboxylic acid ethyl ester 
• 1240402-79-2 [3-(4-Fluoro-phenyl)-5-((E)-styryl)-isoxazol-4-yl]-methanol 
• 1240402-78-1 3-(4-fluoro-phenyl)-5-((E)-styryl)-isoxazole-4-carboxylic acid 
• 1254966-31-8 5-[5-((1S,2R)-1,2-dihydroxy-2-phenyl-ethyl)-3-(4-fluoro-phenyl)-isoxazol-4-ylmethoxy]-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester 
• 52867-42-2 5-hydroxy-2-methyl-2H-pyrazole-3-carboxylic acid methyl ester 

Relevant articles and documents

ISOXAZOLE-PYRAZOLE DERIVATIVES

The present invention is concerned with isoxazole-pyrazole derivatives of formula I, having affinity and selectivity for GABA A α5 receptor, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful as cognitive enhancer or for the therapeutic and/or prophylactic treatment of cognitive disorders like Alzheimer's disease.