1254977-20-2Relevant academic research and scientific papers
[Pd]-Catalyzed Intermolecular Coupling and Acid Mediated Intramolecular Cyclodehydration: One-Pot Synthesis of Indenes
Niharika, Pedireddi,Satyanarayana, Gedu
supporting information, p. 971 - 979 (2018/02/22)
An efficient one-pot synthesis of indenes from simple starting materials is presented. This process involves a dual C–C bond formation through an intermolecular Heck coupling reaction followed by acid-mediated intramolecular cyclodehydration. The strategy
Synthesis of indenes via aluminum chloride-promoted tandem Friedel-Crafts alkylation of arenes and cinnamaldehydes
Kheira, Haiouani,Li, Pingfan,Xu, Jiaxi
, p. 168 - 174 (2014/06/09)
A series of substituted indenes were synthesized from arenes and cinnamaldehydes via aluminum chloride-promoted tandem Friedel-Crafts alkylation. The scope and limitation of the tandem reaction were explored. A plausible reaction mechanism is also discuss
Iodine/Et3SiH: A novel reagent system for the synthesis of 3-aryl-1H-indenes from 1,3-diaryl propargyl alcohols
Reddy, B.V. Subba,Reddy, B. Brahma,Rao, K.V. Raghavendra,Yadav
experimental part, p. 5697 - 5700 (2010/11/05)
1,3-Diaryl propargyl alcohols undergo smooth intramolecular Friedel-Crafts cyclization with triethylsilane in the presence of 10 mol % iodine 3-aryl-1H-indene derivatives in good yields in short reaction times. This is the first example on the synthesis of substituted indenes from 1,3-diaryl propargyl alcohols. The use of inexpensive and readily available molecular iodine makes this method quite simple, more convenient, and practical.
