1255509-72-8Relevant articles and documents
Enantioselective Synthesis of Chromenes via a Palladium-Catalyzed Asymmetric Redox-Relay Heck Reaction
Jiang, Ze-Zhen,Gao, Ang,Li, Hao,Chen, Di,Ding, Chang-Hua,Xu, Bin,Hou, Xue-Long
, p. 3119 - 3122 (2017)
A palladium-catalyzed asymmetric redox-relay Heck reaction of 4H-chromenes and arylboronic acids has been successfully developed. The reaction proceeded in moderate to good yields with good to high enantioselectivities. The resulting product is an advanced intermediate of bio-active compound BW683C.
Iridium-catalyzed asymmetric allylic etherification and ring-closing metathesis reaction for enantioselective synthesis of chromene and 2,5-dihydrobenzo[b]oxepine derivatives
He, Hu,Ye, Ke-Yin,Wu, Qing-Feng,Dai, Li-Xin,You, Shu-Li
supporting information; experimental part, p. 1084 - 1094 (2012/05/20)
Iridium-catalyzed asymmetric etherifications of allylic carbonates with 2-vinylphenols and 2-allylphenols were realized. With a catalyst generated from 2mol% of [Ir(cod)Cl]2 (cod=cycloocta-1,5-diene) and 4mol% of the phosphoramidite ligand L2, the etherification products were obtained in excellent ees and then subjected to the ring-closing metathesis reaction providing an efficient synthesis of enantioenriched 2H-chromene and 2,5-dihydrobenzo[b]oxepine derivatives. Copyright
