695-84-1

Basic information

• Product Name: 2-Hydroxystyrene
• Synonyms: 2-Hydroxystyrene;2-VINYLPHENOL;2-Ethenylphenol
• CAS NO: 695-84-1
• Molecular Formula: C₈H₈O
• Molecular Weight: 120.14852
• Product Categories: Aromatics;Metabolites & Impurities;Mutagenesis Research Chemicals
• Mol File: 695-84-1.mol
• Article Data: 84

Chemical Properties

• Melting Point: 29.5°C
• Boiling Point: 184.15°C (rough estimate)
• Appearance: /
• Density: 1.0609
• Refractive Index: 1.5851
• CAS DataBase Reference: 2-Hydroxystyrene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxystyrene(695-84-1)
• EPA Substance Registry System: 2-Hydroxystyrene(695-84-1)

Safety Data

• Hazardous Substances Data: 695-84-1(Hazardous Substances Data)

Usage

Uses

An oxidative metabolite of Styrene (S687790).

Upstream product

• 75-21-8 oxirane 
• 108-95-2 phenol 
• 122-99-6 2-Phenoxyethanol 
• 496-16-2 2.3-dihydrobenzofuran 
• 50742-63-7 2-(allyloxy)-N,N-dimethylaniline 
• 84809-63-2 Cl-Mo(O)=CH₂ 
• 123-08-0 4-hydroxy-benzaldehyde 
• 78619-10-0 1-vinylbenzene 1,2-oxide 
• 103200-11-9 2-allyloxy-N,N-diethylaniline 
• 102968-97-8 2-allyloxy-S-ethylthiophenol 
• 7664-93-9 sulfuric acid 
• 90-02-8 salicylaldehyde 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 141-82-2 malonic acid 

Downstream Products

• 18732-47-3 3-phenyl-5-(2-hydroxyphenyl)isoxazoline 
• 90-00-6 o-Hydroxyethylbenzene 
• 95123-55-0 2-(2-vinylphenoxy)acetic acid 
• 90151-38-5 2,4-dibromo-6-(1,2-dibromo-ethyl)-phenol 
• 60640-62-2 1-[5-(2-acetoxy-phenyl)-isoxazol-3-yl]-2-bromo-ethanone 
• 60670-03-3 2-bromo-1-[5-(2-acetoxy-phenyl)-4,5-dihydro-isoxazol-3-yl]-ethanone 
• 53983-87-2 2-[3-(1-hydroxy-2-piperidin-1-yl-ethyl)-isoxazol-5-yl]-phenol 
• 1046817-87-1 2-(3-(2-vinylphenoxy)propyl)isoindoline-1,3-dione 
• 1354358-77-2 5-(2-hydroxyphenyl)-3,3-spirocyclobutylbutyrolactone 
• 1510865-01-6 2,3-diphenylbenzo[b]oxepine 
• 1510865-02-7 2,3-bis(4-methoxyphenyl)benzo[b]oxepine 
• 1510865-03-8 2,3-bis(4-(trifluoromethyl)phenyl)benzo[b]oxepine 
• 1510865-07-2 3-ethyl-2-phenylbenzo[b]oxepine 
• 1400999-71-4 3,3,3-trifluoro-1-(2-hydroxyphenyl)propyl 2-iodobenzoate 

Relevant articles and documents

Molecular structure, conformational preferences and vibrational analysis of 2-hydroxystyrene: A computational and spectroscopic research

The molecular structure of 2-hydroxy-styrene has been investigated at DFT (B3LYP, mPW1PW91) and MP2 levels with an assortment of Pople's and Dunning's basis sets within the isolated molecule approximation. The presence of intramolecular hydrogen bonds has

Gold(I)-Catalyzed Intramolecular Dehydrative Amination of Sulfamate Esters Tethered to Allylic Alcohols: A Strategy for the Synthesis of Cyclic Sulfamidates

An efficient synthesis protocol for cyclic sulfamidates has been developed via catalytic intramolecular cyclizations of sulfamate esters tethered to allylic alcohols. The reactions proceed smoothly at room temperature in the presence of (IPr)AuCl (5 mol%) and AgBF4 (5 mol%). This protocol features good to excellent yields, high selectivity, broad substrate scope, and mild reaction conditions. This method is also applicable to the synthesis of a seven-membered sulfamidate. (Figure presented.).

KRAS G12D INHIBITORS

The present invention relates to compounds that inhibit KRas G12D. In particular, the present invention relates to compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor.