1255871-41-0Relevant articles and documents
PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT FACTOR D MEDICAL DISORDERS
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Page/Page column 341; 411, (2020/03/15)
Compounds, methods of use, and processes for making inhibitors of complement factor D or a pharmaceutically acceptable salt or composition thereof are provided. The inhibitors described herein target factor D and inhibit or regulate the complement cascade. The inhibitors of factor D described herein reduce the excessive activation of complement.
NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES
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Page/Page column 147; 148, (2013/03/28)
The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4? R5, R6, R7, A1, A2 and A3 are as described herein, compositions including the compounds and methods of using the compounds.
ARYL PYRIDINE AS ALDOSTERONE SYNTHASE INHIBITORS
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Page/Page column 113, (2012/04/23)
The present invention provides a compound of Formula (I); a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.