125592-05-4

Basic information

• Product Name: 4-hydroxy-3-phenylindan-1-one
• CAS NO: 125592-05-4
• Molecular Weight: 224.259
• Mol File: 125592-05-4.mol

Chemical Properties

• CAS DataBase Reference: 4-hydroxy-3-phenylindan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-hydroxy-3-phenylindan-1-one(125592-05-4)
• EPA Substance Registry System: 4-hydroxy-3-phenylindan-1-one(125592-05-4)

Safety Data

• Hazardous Substances Data: 125592-05-4(Hazardous Substances Data)

Upstream product

• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 100-52-7 benzaldehyde 
• 22966-24-1 (E)-1-(3-methoxyphenyl)-3-phenylprop-2-en-1-one 
• 3033-92-9 1-(3-hydroxyphenyl)-3-phenyl-2-propen-1-one 

Relevant articles and documents

Reactive Annulenones: A Comparative Study

Two new and hitherto elusive annulenones, 3-phenylcyclopentadienone and bicycloocta-1(5),3,6-triene-2,8-dione, are reported.Their lifetimes and reactivities have been studied in comparison with those of the related annulenones cyclopentadienone and 4-phenylbicycloocta-1(5),3,6-triene-2,8-dione.The influence of structure and substituents on the stabilities of these species has thereby been established.

Intramolecular Alkylation of Phenols. Part 4. Base-catalysed Cyclisation of Phenolic Enones. Scope and Limitations

The phenolic enones (4), (5), (8), (9), and (13) cyclise readily under acidic conditions.However, neither these nor the thio-substituted phenols (11a), (13a), (14a), and (15a) closed under basic conditions.Involvement of unfavourable equilibria is disproved.Comparison is made with related successful cyclisations of the saturated ketone (38) and aldehyde (39).Preliminary results suggest that strict stereo-electronic requirements are necessary for enone ring closure and that these conditions are not met in base-catalysed 5-Endo- and 6-Endo-Trigonal ring closures of the phenols of general type (2; n=0 and n=1).