1255944-41-2Relevant academic research and scientific papers
Enantioselective separation of (±)-β-hydroxy-1,2,3-triazoles by supercritical fluid chromatography and high-performance liquid chromatography
Alvarenga, Natália,Porto, André L.M.,Barreiro, Juliana Cristina
, p. 890 - 899 (2018/04/30)
This paper reports the enantioseparation of β-hydroxy-1,2,3-triazole derivatives, which present a broad range of biological properties, by supercritical fluid chromatography (SFC) and high-performance liquid chromatography techniques (HPLC). Polysaccharid
Catalytic asymmetric synthesis of β-triazolyl amino alcohols by asymmetric transfer hydrogenation of α-triazolyl amino alkanones
Vyas, Vijyesh K.,Bhanage, Bhalchandra M.
, p. 974 - 982 (2017/07/11)
The synthesis of optically active β-triazolyl amino alcohols was carried out via ruthenium catalyzed asymmetric transfer hydrogenation of α-triazolyl amino alkanones. This reaction proceeds under mild reaction conditions with up to 99% yield and 99.9% ena
Combining designer cells and click chemistry for a one-pot four-step preparation of enantiopure β-hydroxytriazoles
Szymanski, Wiktor,Postema, Christiaan P.,Tarabiono, Chiara,Berthiol, Florian,Campbell-Verduyn, Lachlan,De Wildeman, Stefaan,De Vries, Johannes G.,Feringa, Ben L.,Janssen, Dick B.
supporting information; experimental part, p. 2111 - 2115 (2010/11/04)
The multistep catalytic process using designer cells, either added as freshly prepared suspensions or as stable lyophilized powder, and click reaction can be performed in one pot. The sequence of four reactions allows the production of both enantiomers of β-hydroxytriazoles with high enantiomeric excess.
One pot 'click' reactions: Tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition
Campbell-Verduyn, Lachlan S.,Szymanski, Wiktor,Postema, Christiaan P.,Dierckx, Rudi A.,Elsinga, Philip H.,Janssen, Dick B.,Feringa, Ben L.
scheme or table, p. 898 - 900 (2010/06/12)
Halohydrin dehalogenase (HheC) can perform enantioselective azidolysis of aromatic epoxides to 1,2-azido alcohols which are subsequently ligated to alkynes producing chiral hydroxy triazoles in a one-pot procedure with excellent enantiomeric excess. The Royal Society of Chemistry 2010.
