1256240-40-0

Basic information

• Product Name: (3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol hydrochloride
• Synonyms: (3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol hydrochloride;(3aR,5b,6aS)-rel-Octahydrocyclopenta[c]pyrrol-5-ol hydrochloride;(3aalpha,5beta,6aalpha)-Octahydrocyclopenta[c]pyrrol-5-ol hydrochloride (1:1)
• CAS NO: 1256240-40-0
• Molecular Formula: C₇H₁₃NO*ClH
• Molecular Weight: 163.64516
• Mol File: 1256240-40-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol hydrochloride(1256240-40-0)
• EPA Substance Registry System: (3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol hydrochloride(1256240-40-0)

Safety Data

• Hazardous Substances Data: 1256240-40-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
(3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol hydrochloride is used as a lead compound for drug development due to its pharmacological activities, including anti-inflammatory and cytotoxic properties. Its unique structure and potential therapeutic applications make it a promising candidate for the treatment of various diseases.
Used in Medicinal Chemistry Research:
(3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol hydrochloride is used as a subject of study in medicinal chemistry research to explore its structure-activity relationships, optimize its pharmacological properties, and develop new drugs with improved efficacy and safety profiles.
Used in Synthetic Chemistry Research:
(3aR,5r,6aS)-octahydrocyclopenta[c]pyrrol-5-ol hydrochloride is used as a target molecule in synthetic chemistry research to develop novel synthetic routes and methods for its preparation, modification, and functionalization, enabling the exploration of its potential applications in various fields.

Upstream product

• 146231-54-1 (3aR,6aS)-tert-butyl 5-oxohexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 
• 912563-45-2 tert-butyl (3aR,5r,6aS)-5-hydroxy-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxylate 

Downstream Products

• 1256240-42-2 [3-(ethoxycarbonyl)isoxazol-5-yl]methyl (3aR,5s,6aS)-5-(4-bromophenoxy)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS COMPRISING THE HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF

(I) Disclosed herein are compounds of formula I, and/or a stereoisomer, a stable isotope, or a pharmaceutically acceptable salt or solvate thereof; and therapeutic uses of these compounds, which are inhibitors of rearranged during transfection (RET), potentially useful in the treatment of RET-associated diseases, such as RET-associated cancers.

4-quinazoline amine derivatives and their use

A 4-quinazoline amine derivative as represented by formula (1), a pharmaceutical composition comprising the derivative, and an application thereof in preparing medicine for curing cancer. The cancer is a drug-resistant cancer, preferably a cancer resisting an EGFR reversible inhibitor, and more preferably, a cancer resisting gefitinib, erlotinib or lapatinib; alternatively, the cancer carries EGFR mutation.

CYCLOPENTA[C]PYRROLE-2-CARBOXYLATE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The invention relates to compounds of the general formula (I) where: R2 is a hydrogen or fluorine atom or a hydroxyl, cyano, trifluoromethyl, C1-6-alkyl, C1-6-alkoxy, or NR8R9 group; m, n, o and p ind