1256338-97-2

Upstream product

• 20698-91-3 (R)-methyl mandelate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 130115-07-0 (R)-2-(t-butyldimethylsilyloxy)-2-phenylacetaldehyde 
• 124876-74-0 Methyl (R)-(-)-α-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-α-phenylacetate 
• 179618-33-8 ethyl (2E,4S)-4-{[(tert-butyl)(dimethyl)silyl]oxy}-4-phenylbut-2-enoate 
• 179618-34-9 ethyl (2S,3S,4R)-4-{[(tert-butyl)(dimethyl)silyl]oxy}-2,3-dihydroxy-4-phenylbutanoate 
• 187931-99-3 ethyl (4S,5S)-5-[(R)-{[(tert-butyl)(dimethyl)silyl]oxy}(phenyl)methyl]-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 338385-70-9 (4S,5S)-5-[(R)-(tert-Butyl-dimethyl-silanyloxy)-phenyl-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 
• 1256338-96-1 (1R,2S,3R)-5-(benzyloxy)-1-(tert-butyldimethylsiloxy)-2,3-(isopropylidenedioxy)-1-phenylpentane 

Downstream Products

• 246035-59-6 (4S,6R)-6-[(1R,2R)-1,2-dihydroxy-2-phenylethyl]-4-hydroxy-tetrahydro-2H-2-pyranone 

Relevant academic research and scientific papers

Concise stereoselective total synthesis of leiocarpin C

A simple and highly concise strategy has been developed for the stereoselective total synthesis of leiocarpin C starting from commercially available mandelic ester. The strategy utilizes the OsO4-catalyzed cis-hydroxylation and selective reduction with K-Selectride as key steps. Copyright

Stereoselective total synthesis of leiocarpin C and (+)-goniodiol

Total syntheses of styryl lactones, leiocarpin C and (+)-goniodiol have been accomplished in a highly stereoselective manner. The key steps involved in these syntheses are the Chan alkyne reduction, Sharpless asymmetric dihydroxylation, Horner-Wadsworth-E