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4-bromo-3-methoxyphenylboronic acid is a boronic acid derivative with the molecular formula C7H8BBrO3. It features a phenyl ring with a bromine atom at the 4-position and a methoxy group at the 3-position. This chemical compound is widely used in organic synthesis and medicinal chemistry as a versatile building block for the creation of pharmaceuticals and agrochemicals.

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  • 1256345-59-1 Structure
  • Basic information

    1. Product Name: 4-bromo-3-methoxyphenylboronic acid
    2. Synonyms: 4-bromo-3-methoxyphenylboronic acid
    3. CAS NO:1256345-59-1
    4. Molecular Formula: C7H8BBrO3
    5. Molecular Weight: 230.85162
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1256345-59-1.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Room temperature.
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-bromo-3-methoxyphenylboronic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-bromo-3-methoxyphenylboronic acid(1256345-59-1)
    11. EPA Substance Registry System: 4-bromo-3-methoxyphenylboronic acid(1256345-59-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1256345-59-1(Hazardous Substances Data)

1256345-59-1 Usage

Uses

Used in Organic Synthesis:
4-bromo-3-methoxyphenylboronic acid is used as a building block in organic synthesis for the creation of various pharmaceuticals and agrochemicals. Its unique structure allows for the formation of carbon-carbon bonds through Suzuki-Miyaura cross-coupling reactions, making it a valuable reagent in this field.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 4-bromo-3-methoxyphenylboronic acid is utilized in the development of potential drugs for the treatment of various diseases. Its ability to form carbon-carbon bonds and its unique functional groups make it an important compound for designing and synthesizing novel therapeutic agents.
Used in Suzuki-Miyaura Cross-Coupling Reactions:
4-bromo-3-methoxyphenylboronic acid is used as a reagent in Suzuki-Miyaura cross-coupling reactions, which are crucial for creating carbon-carbon bonds in organic synthesis. This reaction allows for the formation of complex molecular structures, making it an essential tool in the synthesis of pharmaceuticals and agrochemicals.
Overall, 4-bromo-3-methoxyphenylboronic acid is a versatile and valuable compound in the fields of organic synthesis and medicinal chemistry, playing a significant role in the development of new pharmaceuticals and agrochemicals through its use in Suzuki-Miyaura cross-coupling reactions and as a building block for various applications.

Check Digit Verification of cas no

The CAS Registry Mumber 1256345-59-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,6,3,4 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1256345-59:
(9*1)+(8*2)+(7*5)+(6*6)+(5*3)+(4*4)+(3*5)+(2*5)+(1*9)=161
161 % 10 = 1
So 1256345-59-1 is a valid CAS Registry Number.

1256345-59-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromo-3-methoxyphenylboronic acid

1.2 Other means of identification

Product number -
Other names (4-Bromo-3-methoxyphenyl)boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1256345-59-1 SDS

1256345-59-1Downstream Products

1256345-59-1Relevant articles and documents

HETEROCYCLIC COMPOUNDS AND METHODS OF USE

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Paragraph 0294, (2015/05/05)

The present application discloses compounds that are inhibitors of Btk, compounds that are inhibitors of ΡΒΚδ, and compounds that are dual inhibitors of both Btk and PI3Kδ. Also described are methods for synthesizing such inhibitors and methods for using such inhibitors for the treatment of diseases wherein inhibition of Btk and PI3Kδ provides a therapeutic benefit to a patient having the disease.

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