1256346-79-8Relevant academic research and scientific papers
Development of a practical synthesis of a pyrazolopyridinone-based p38 MAP kinase inhibitor
Milburn, Robert R.,Thiel, Oliver R.,Achmatowicz, Michal,Wang, Xiang,Zigterman, Jamie,Bernard, Charles,Colyer, John T.,Divirgilio, Evan,Crockett, Rich,Correll, Tiffany L.,Nagapudi, Karthik,Ranganathan, Kumar,Hedley, Simon J.,Allgeier, Alan,Larsen, Robert D.
, p. 31 - 43 (2011)
A practical synthesis of the pyrazolopyridinone-based p38 MAP kinase inhibitor (4) was required for an ongoing program. The synthesis of a key pyrazolopyridinone building block was refined and optimized to provide kilogram quantities of 10 without chromat
