1256359-99-5

Basic information

• Product Name: 1-Boc-5-Methoxyindole-3-boronic acid, pinacol ester
• Synonyms: 1-Boc-5-Methoxyindole-3-boronic acid, pinacol ester;tert-Butyl 5-methoxy-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole-1-carboxylate
• CAS NO: 1256359-99-5
• Molecular Formula: C₂₀H₂₈BNO₅
• Molecular Weight: 391.2663
• Mol File: 1256359-99-5.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-Boc-5-Methoxyindole-3-boronic acid, pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Boc-5-Methoxyindole-3-boronic acid, pinacol ester(1256359-99-5)
• EPA Substance Registry System: 1-Boc-5-Methoxyindole-3-boronic acid, pinacol ester(1256359-99-5)

Safety Data

• Hazardous Substances Data: 1256359-99-5(Hazardous Substances Data)

Usage

General Description

1-Boc-5-Methoxyindole-3-boronic acid, pinacol ester is a chemical compound that is commonly used in organic synthesis. It is a boronic acid ester, which is an important class of compounds in organic chemistry. This particular compound is often used as a building block in the synthesis of various pharmaceuticals and other organic molecules. The "Boc" group in the compound refers to tert-butoxycarbonyl, which is a protective group commonly used in organic chemistry to protect amines and other reactive functional groups. The pinacol ester portion of the compound refers to a specific type of boronic acid ester, which is widely used in Suzuki coupling reactions to form carbon-carbon bonds. Overall, 1-Boc-5-Methoxyindole-3-boronic acid, pinacol ester is a versatile and important compound in the field of organic chemistry.

Upstream product

• 99275-47-5 1-(tert-butyloxycarbonyl)-5-methoxyindole 
• 73183-34-3 bis(pinacol)diborane 
• 348640-11-9 tert-butyl 3-bromo-5-methoxy-1H-indole-1-carboxylate 
• 192189-10-9 3-iodo-5-methoxyindole-1-carboxylic acid tert-butyl ester 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 85092-86-0 3-iodo-5-methoxy-1H-indole 
• 1006-94-6 5-methoxylindole 

Downstream Products

• 1310704-53-0 tert-butyl 5-methoxy-3-(1-methyl-6-tosyl-1,6-dihydropyrazolo[3,4-d]pyrrolo[2,3-b]pyridin-7-yl)-1H-indole-1-carboxylate 
• 1350378-16-3 tert-butyl 3-(5-fluoro-4-(2-(1-hydroxycyclobutyl)thiazol-5-yl)-1-tosyl-1H-pyrrolo[2,3-b]pyridin-2-yl)-5-methoxy-1H-indole-1-carboxylate 

Relevant articles and documents

Synthesis of scalaridine A

A synthesis of the pyridine-linked bisindole alkaloid scalaridine A is described. An iridium catalyzed, directed C-H borylation of N-Boc-5-methoxyindole gave the corresponding 3-borylindole, which underwent a one-pot, double Suzuki-Miyaura cross-coupling reaction with 3,5-dibromopyridine to install the entire heteroaromatic framework of the natural product. Removal of the protecting groups gave a synthetic sample of scalaridine A, which was spectroscopically identical to that described in the isolation report.

Hyrtinadine alkaloid derivative as well as preparation and application of Hyrtinadine alkaloid derivative in resisting plant viruses and germs

The invention relates to a Hyrtinadine alkaloid derivative as well as preparation and application of the Hyrtinadine alkaloid derivative in resisting plant viruses and germs. The Hyrtinadine alkaloidderivative shows especially excellent plant virus resist

PYRROLOPYRIDINE AND PYRROLOPYRIMIDINE INHIBITORS OF KINASES

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, B, R1, R2, R3, R4a, R5, and Z are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as aurora.