125641-39-6

Upstream product

• 764-13-6 2,5-Dimethyl-2,4-hexadiene 
• 125640-92-8 2,6-di-tert-butyl-4-methylphenyl diazoacetate 
• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 
• 125641-00-1 2,6-Bis(1,1-dimethylethyl)-4-methylphenyl 2-diazo-3-butenoate 

Relevant academic research and scientific papers

Asymmetric Copper-Catalyzed Cyclopropanation of Trisubstituted and Unsymmetrical cis-1,2-Disubstituted Olefins: Modified Bis-Oxazoline Ligands

The Cu(I) complexes of new bis-oxazolines (3-7) prepared from the corresponding amino alcohols and malono-bis-imidate exhibit high enantioselectivity of up to 94 percent ee in the catalytic cyclopropanation of trisubstituted and unsymmetrical cis-1,2-disubstituted olefins.New diazoacetate reagents have also been developed giving high trans/cis ratios of up to 99:1 trans.

Exceptionally high trans (anti) stereoselectivity in catalytic cyclopropanation reactions

Exceptionally high trans (anti) stereoselectivities are obtained in rhodium(II) carboxylate and carboxamide catalyzed alkene cyclopropanation reactions with 2,6-di-tert-butyl-4-methylphenyl diazoacetate (BDA). With monosubstituted ethylenes, use of rhodiu