125643-07-4

Upstream product

• 2930-05-4 (S)-benzyl glycidyl ether 
• 116-11-0 2-Methoxypropene 
• 125782-68-5 (S)-1-Benzyloxy-3-(5-hydroxymethyl-furan-2-yl)-propan-2-ol 

Downstream Products

• 125643-03-0 (1R,5S,11R)-5-<(Benzyloxy)methyl>-11-<(1E,4S)-5-<(tert-butyldimethylsilyl)oxy>-2,4-dimethyl-1-pentenyl>-3,3-dimethyl-2,4,7-trioxaspiro<5.5>undecan-9-one 
• 125782-72-1 (4R,6S,9R,11S)-4-Benzyloxymethyl-9-iodo-2,2-dimethyl-11-vinyl-1,3,7-trioxa-spiro[5.5]undecane 
• 125782-74-3 (2R,5S)-1-Benzyloxy-2-hydroxy-5-vinyl-oct-7-en-4-one 

Relevant academic research and scientific papers

Methodology for the Enantioselective Synthesis of Aldols and Other 1,3-Dioxygenated Systems

The enantioselective synthesis of the spiroenones 3, 4 from (S)-glycidol-O-benzyl ether and lithiated furan derivatives is described.After conjugate addition of lithium dimethyl cuprate or lithium divinyl cuprate and conversion of the resulting saturated ketones to their respective iodides 7 and 8, fragmentation of these halides leads to the formation of acyclic aldol-containing carbon skeletons.