125643-35-8Relevant articles and documents
Radical-Mediated Heck-Type Alkylation: Stereoconvergent Synthesis of Functionalized Polyenes
Zhang, Hong,Wu, Xinxin,Wei, Yunlong,Zhu, Chen
supporting information, p. 7568 - 7572 (2019/10/02)
The stereospecific synthesis of polyenes is of great synthetic value. Disclosed herein is a new, efficient, stereoconvergent approach for the synthesis of functionalized polyenes via a radical-mediated Heck-type alkylation. The easily accessed Z- and E-mixed alkenes are harnessed as starting material, leading to a unique stereoisomer of polyenes. In addition, the transformation features mild reaction conditions and broad functional group compatibility. A variety of valuable 1,3-dienes and 1,3,5-trienes are afforded in useful yields.
A visible-light-mediated oxidative C-N bond formation/aromatization cascade: Photocatalytic preparation of N-arylindoles
Maity, Soumitra,Zheng, Nan
supporting information, p. 9562 - 9566 (2012/11/07)
Just add light and air: Structurally diverse N-arylindoles can be prepared from readily prepared o-styryl anilines through visible-light photocatalysis. The reaction, which is conducted open to air, is mediated by [Ru(bpz) 3](PF6)2 (bpz=2,2'-bipyrazine) and involves both C-N bond formation and aromatization (see scheme). Using suitably substituted substrates, a 1,2-carbon shift can be also incorporated into this cascade reaction. Copyright
Design of 1,2-dioxines with anti-Candida activity: aromatic substituted 1,2-dioxines
Macreadie, Ian G.,Avery, Thomas D.,Robinson, Tony V.,Macreadie, Peter,Barraclough, Miles,Taylor, Dennis K.,Tiekink, Edward R.T.
, p. 1225 - 1232 (2008/09/17)
In an ongoing effort to rationally design new antimicrobials, 47 new 1,2-dioxines have been synthesised. Broad antifungal structure-activity relationships governing aromatically substituted epoxy-1,2-dioxines 2 and 3 and their parent 1,2-dioxines 1 were a
