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Usage

Uses

Used in Organic Chemistry Research:
1-(2-bromophenyl)but-3-en-1-ol is used as a research compound in the field of organic chemistry for studying its aromatic and organic functional group properties. Its unique structure allows for the exploration of various chemical reactions and interactions with other compounds.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 1-(2-bromophenyl)but-3-en-1-ol is used as a starting material for the synthesis of various pharmaceuticals and organic compounds. Its bromine-substituted phenyl group and butenol structure provide a foundation for the development of new drugs and medicinal agents.
Used in Chemical Synthesis:
1-(2-bromophenyl)but-3-en-1-ol is also utilized in the synthesis of other organic compounds, contributing to the development of new materials and products in various industries, such as plastics, dyes, and coatings. Its unique structure and properties make it a valuable building block for creating novel compounds with specific applications.

Upstream product

• 762-73-2 trimethyl(allyl)stannane 
• 6630-33-7 ortho-bromobenzaldehyde 
• 1730-25-2 allylmagnesium bromide 
• 24850-33-7 allyltributylstanane 
• 556-56-9 allyl iodid 
• 106-95-6 allyl bromide 
• 107-18-6 allyl alcohol 
• 591-87-7 Allyl acetate 
• 2622-05-1 allylmagnesium bromide 
• 1162681-59-5 4-(2-bromophenyl)-4-trimethylsiloxy-1-butene 
• 18982-54-2 o-bromobenzyl alcohol 

Downstream Products

• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 22339-44-2 2,3-dihydro-3-methyl-1H-inden-1-ol 
• 1006-18-4 cis-3-methyl-2,3-dihydro-1H-inden-1-ol 
• 1006-18-4 3-methyl-2,3-dihydro-1H-inden-1-ol 
• 1026779-16-7 (E)-1-bromo-2-(3-methoxybut-1-enyl)benzene 
• 125643-35-8 1-bromo-2-(buta-1,3-dien-1-yl)benzene 
• 1210066-94-6 (E)-4-(2-bromophenyl)-4-hydroxybut-2-enyl propionate 
• 1620206-31-6 (E)-N-(1-bromo-4-(2-bromophenyl)but-3-en-2-yl)-2,2,2-trichloroacetamide 
• 1620206-14-5 C₁₂H₁₁BrCl₃NO 
• 1584149-43-8 1,1-dimethyl-3-(3-(4-vinylphenyl)propyl)-1,3-dihydrobenzo[c]-[1,2]oxasilole 
• 1584149-42-7 3-(3-(4-bromophenyl)propyl)-1,1-dimethyl-1,3-dihydrobenzo[c]-[1,2]oxasilole 

Relevant academic research and scientific papers

SYNTHESIS OF 4,8-DIHYDROXY-3-METHYL-5,6-BENZO-2-OXABICYCLOOCT-5-ENE

The title compound having the same relative configuration as granaticin(1) and U-58,431(2) was prepared either by dehydrogenative cyclization of the precursor 9a or by pinacol cyclization of the dicarbonyl compound 15.

Copper-Impregnated Magnesium-Lanthanum Mixed Oxide: A Reusable Heterogeneous Catalyst for Allylation of Aldehydes and Ketones

Copper-impregnated magnesium-lanthanum mixed oxide [Cu(II)/Mg?La] was used as catalyst in synthesis of homoallylic alcohols from aldehydes and ketones using allyltributylstannane as the allylating source. The present protocol provides a great application

Cationic Cobalt Porphyrin-Catalyzed Allylation of Aldehydes with Allyltrimethylsilanes

Cationic cobalt porphyrin-catalyzed allylation of aldehydes with allyltrimethylsilanes is developed. The formation of the aldehyde-cobalt porphyrin complex, the key intermediate for the addition of allylsilanes, is confirmed by theoretical studies and syn

Catalytic Nucleophilic Allylation Driven by the Water-Gas Shift Reaction

The ruthenium-catalyzed allylation of aldehydes with allylic pro-nucleophiles has been demonstrated to be an efficient means to form carbon-carbon bonds under mild conditions. The evolution of this reaction from the initial serendipitous discovery to its general synthetic scope is detailed, highlighting the roles of water, CO, and amine in the generation of a more complete catalytic cycle. The use of unsymmetrical allylic pro-nucleophiles was shown to give preferential product formation through the modulation of reaction conditions. Both (E)-cinnamyl acetate and vinyl oxirane were efficiently used to form the anti-branched products (up to >20:1 anti/syn) and E-linear products (up to >20:1 E/Z) in high selectivity with aromatic, α,β-unsaturated, and aliphatic aldehydes, respectively. Attempts to render the reaction enantioselective are highlighted and include enantioenrichment of up to 75:25 for benzaldehyde.

Design, Synthesis, and Application of Polymer-Supported Silicon-Transfer Agents for Cross-Coupling Reactions with Organolithium Reagents

The initial design, synthesis, and validation of polymer-supported siloxane transfer agents have been achieved that permit the direct use of organolithium reagents in the palladium-catalyzed cross-coupling reactions. Through rational design, two generations of polymer support were developed that significantly simplify product purification and the transfer agent recycling.

Green Organocatalytic Dihydroxylation of Alkenes

An inexpensive, green, metal-free one-pot procedure for the dihydroxylation of alkenes is described. H2O2 and 2,2,2-trifluoroacetophenone were employed as the oxidant and organocatalyst, respectively, in this highly sustainable protocol in which a variety of homoallylic alcohols, aminoalkenes, and simple alkenes were converted into the corresponding polyalcohols in good to excellent yields. This process takes advantage of an epoxidation reaction followed by an acidic treatment in which water participates in the ring opening of the in situ prepared epoxide to lead to the desired product.

Palladacycles having normal and spiro chelate rings designed from bi- and tridentate ligands with an indole core: Structure, synthesis and applications as catalysts

1-Pyridin-2-ylmethyl-1H-indole-3-carbaldehyde and 1-((1-benzyl-1H-1,2,3-triazol-4-yl)methyl)-1H-indole-3-carbaldehyde were synthesized. Their condensation with benzyl amine resulted in indole core containing Schiff bases benzyl-(1-pyridin-2-ylmethyl-1H-in

Ter-pyridine catalyzed allylation of aldehydes and ketones under metal-free condition

Ter-pyridine derivatives were found to be potential catalyst for homoallylation of carbonyl groups. High yields of the products with short reaction times of ～2 h were observed in several cases. These new catalysts work efficiently with the simple reagent such as allyl magnesium bromide and hence can avoid the use of other sensitive or toxic reagents. It was found that the presence of polar groups on the catalysts made them extremely efficient without the presence of any metal salts.

Palladacycles of unsymmetrical (N,C-,E) (E = S/Se) pincers based on indole: Their synthesis, structure and application in the catalysis of Heck coupling and allylation of aldehydes

Unsymmetrical (N,C,E)-type pincer ligand precursors [L1 and L2: E = S/Se] with an indole core were synthesized for the first time by the condensation of 1-(2-phenylsulfanyl/selenylethyl)-1H-indole-3-carbaldehyde with benzyl amine. The synthetic protocols

Cu-MEDIATED ANNULATION FOR THE EFFECTIVE SYNTHESIS OF 3-SUBSTITUTED PHTHALIDES

The present invention disclosed herein is a novel commercially feasible, one pot synthesis of library of 3-substituted phthalides of formula I via CuCN mediated oxidative cyclization in high yield. Formula I