1256553-91-9Relevant academic research and scientific papers
Tandem multicomponent reactions toward the design and synthesis of novel antibacterial and cytotoxic motifs
Semreen, Mohammad H.,El-Awady, Raafat,Abu-Odeh, Raed,Saber-Ayada, Maha,Al-Qawasmeh, Raed A.,Chouaib, Salem,Voelter, Wolfgang,Al-Tel, Taleb H.
, p. 1445 - 1459 (2013/07/28)
The synthesis of polysubstituted imidazopyridines and imidazopyrazines through the orthogonal union of Groebke-Blackburn and Ugi reactions is described. These motifs were produced efficiently in a tandem operation without intermediate isolation. The synth
Rapid assembly of polyfunctional structures using a one-pot five- and six-component sequential Groebke-Blackburn/Ugi/Passerini process
Al-Tel, Taleb H.,Al-Qawasmeh, Raed A.,Voelter, Wolfgang
experimental part, p. 5586 - 5593 (2011/02/22)
Sequential addition of up to six components under well-defined conditions results in the formation of novel structures with amino acid, peptide, and heterocyclic components. This process forms up to eight new bonds under very mild conditions and tolerates
