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1256824-48-2

1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1256824-48-2 Structure

  • Basic information

    1. Product Name: 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
    2. Synonyms: 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester;Ethyl 1H-pyrazolo[3,4-b]pyridine-5-carboxylate
    3. CAS NO:1256824-48-2
    4. Molecular Formula: C9H9N3O2
    5. Molecular Weight: 191.18666
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1256824-48-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 345.3±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.339±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 8.72±0.40(Predicted)
    10. CAS DataBase Reference: 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester(1256824-48-2)
    12. EPA Substance Registry System: 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester(1256824-48-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1256824-48-2(Hazardous Substances Data)

1256824-48-2 Usage

Molecular Weight

206.19 g/mol

Chemical Class

Pyrazole

Biological Activities

Anti-inflammatory, anti-cancer, and anti-bacterial properties

Common Uses

Building block for the synthesis of various bioactive molecules and pharmaceutical drugs

Ethyl Ester Form

Versatile and easily manipulable compound for chemical reactions

Importance

Potential in drug development and has been the subject of numerous research studies for the development of new and improved pharmaceuticals in the future.

Check Digit Verification of cas no

The CAS Registry Mumber 1256824-48-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,6,8,2 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1256824-48:
(9*1)+(8*2)+(7*5)+(6*6)+(5*8)+(4*2)+(3*4)+(2*4)+(1*8)=172
172 % 10 = 2
So 1256824-48-2 is a valid CAS Registry Number.

1256824-48-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 1H-pyrazolo[3,4-b]pyridine-5-carboxylate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1256824-48-2 SDS

1256824-48-2Relevant articles and documents

Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5- carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)

Zheng, Xiaozhang,Bair, Kenneth W.,Bauer, Paul,Baumeister, Timm,Bowman, Krista K.,Buckmelter, Alexandre J.,Caligiuri, Maureen,Clodfelter, Karl H.,Feng, Yezhen,Han, Bingsong,Ho, Yen-Ching,Kley, Nikolai,Li, Hong,Liang, Xiaorong,Liederer, Bianca M.,Lin, Jian,Ly, Justin,O'Brien, Thomas,Oeh, Jason,Oh, Angela,Reynolds, Dominic J.,Sampath, Deepak,Sharma, Geeta,Skelton, Nicholas,Smith, Chase C.,Tremayne, Jarrod,Wang, Leslie,Wang, Weiru,Wang, Zhongguo,Wu, Hongxing,Wu, Jiansheng,Xiao, Yang,Yang, Guangxing,Yuen, Po-Wai,Zak, Mark,Dragovich, Peter S.

supporting information, p. 5488 - 5497 (2013/10/01)

Potent, 1H-pyrazolo[3,4-b]pyridine-containing inhibitors of the human nicotinamide phosphoribosyltransferase (NAMPT) enzyme were identified using structure-based design techniques. Many of these compounds exhibited nanomolar antiproliferation activities a

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