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1453174-77-0

1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 4-(4-oxetan-3-ylpiperazine-1-sulfonyl)benzylamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 4-(4-oxetan-3-ylpiperazine-1-sulfonyl)benzylamide

    Cas No: 1453174-77-0

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  • 1453174-77-0 Structure

  • Basic information

    1. Product Name: 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 4-(4-oxetan-3-ylpiperazine-1-sulfonyl)benzylamide
    2. Synonyms:
    3. CAS NO:1453174-77-0
    4. Molecular Formula:
    5. Molecular Weight: 456.525
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1453174-77-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 4-(4-oxetan-3-ylpiperazine-1-sulfonyl)benzylamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 4-(4-oxetan-3-ylpiperazine-1-sulfonyl)benzylamide(1453174-77-0)
    11. EPA Substance Registry System: 1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid 4-(4-oxetan-3-ylpiperazine-1-sulfonyl)benzylamide(1453174-77-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1453174-77-0(Hazardous Substances Data)

1453174-77-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1453174-77-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,3,1,7 and 4 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1453174-77:
(9*1)+(8*4)+(7*5)+(6*3)+(5*1)+(4*7)+(3*4)+(2*7)+(1*7)=160
160 % 10 = 0
So 1453174-77-0 is a valid CAS Registry Number.

1453174-77-0Downstream Products

1453174-77-0Relevant articles and documents

Identification of amides derived from 1H-pyrazolo[3,4-b]pyridine-5- carboxylic acid as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)

Zheng, Xiaozhang,Bair, Kenneth W.,Bauer, Paul,Baumeister, Timm,Bowman, Krista K.,Buckmelter, Alexandre J.,Caligiuri, Maureen,Clodfelter, Karl H.,Feng, Yezhen,Han, Bingsong,Ho, Yen-Ching,Kley, Nikolai,Li, Hong,Liang, Xiaorong,Liederer, Bianca M.,Lin, Jian,Ly, Justin,O'Brien, Thomas,Oeh, Jason,Oh, Angela,Reynolds, Dominic J.,Sampath, Deepak,Sharma, Geeta,Skelton, Nicholas,Smith, Chase C.,Tremayne, Jarrod,Wang, Leslie,Wang, Weiru,Wang, Zhongguo,Wu, Hongxing,Wu, Jiansheng,Xiao, Yang,Yang, Guangxing,Yuen, Po-Wai,Zak, Mark,Dragovich, Peter S.

, p. 5488 - 5497 (2013/10/01)

Potent, 1H-pyrazolo[3,4-b]pyridine-containing inhibitors of the human nicotinamide phosphoribosyltransferase (NAMPT) enzyme were identified using structure-based design techniques. Many of these compounds exhibited nanomolar antiproliferation activities a

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