125718-81-2

Basic information

• Product Name: (5-{(S)-2-[2-(2,4-Bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentyl)-carbamic acid tert-butyl ester
• Synonyms: (5-{(S)-2-[2-(2,4-Bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentyl)-carbamic acid tert-butyl ester
• CAS NO: 125718-81-2
• Molecular Weight: 646.784
• Mol File: 125718-81-2.mol

Chemical Properties

• CAS DataBase Reference: (5-{(S)-2-[2-(2,4-Bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentyl)-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (5-{(S)-2-[2-(2,4-Bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentyl)-carbamic acid tert-butyl ester(125718-81-2)
• EPA Substance Registry System: (5-{(S)-2-[2-(2,4-Bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentyl)-carbamic acid tert-butyl ester(125718-81-2)

Safety Data

• Hazardous Substances Data: 125718-81-2(Hazardous Substances Data)

Upstream product

• 462-94-2 1,5-diaminopentane 
• 125718-80-1 [5-((S)-2-Amino-3-carbamoyl-propionylamino)-pentyl]-carbamic acid tert-butyl ester 
• 113978-98-6 dibenzyl-2,4-dihydroxyphenylacetic acid N-hydroxysuccinimide ester 
• 121903-72-8 1-(2,4-Bis-benzyloxy-phenyl)-2-diazo-ethanone 
• 121903-71-7 2,4-bis(benzyloxy)benzoyl chloride 
• 85593-77-7 2,4-bis(benzyloxy)benzoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 174623-83-7 [5-((S)-2-Benzyloxycarbonylamino-3-carbamoyl-propionylamino)-pentyl]-carbamic acid tert-butyl ester 
• 51644-96-3 5-tert-butoxycarbonylamino-1-aminopentane 

Downstream Products

• 125739-24-4 (S)-N¹-(5-{3-[4-((S)-2-Amino-5-guanidino-pentanoylamino)-butylamino]-propionylamino}-pentyl)-2-[2-(2,4-dihydroxy-phenyl)-acetylamino]-succinamide; hydrochloride 
• 113954-15-7 (S)-N¹-(5-Amino-pentyl)-2-[2-(2,4-bis-benzyloxy-phenyl)-acetylamino]-succinamide 
• 125718-78-7 (S)-N¹-(5-Amino-pentyl)-2-[2-(2,4-bis-benzyloxy-phenyl)-acetylamino]-succinamide; hydrochloride 

Relevant articles and documents

Practical, convergent total synthesis of polyamine amide spider toxin NSTX-3

A practical, total synthesis of polyamine amide spider toxin NSTX-3, a potent glutamate receptor antagonist with potential as a neuroprotective agent, is reported. The unsymmetrical polyamine moiety was built by a conjugate addition to afford putreanine and regioselective acylation of L-asparaginyl-cadaverine.

Synthesis of Neurotoxic Nephila Spider Venoms: NSTX-3 and JSTX-3

Efficient and practical synthetic routes to the polyamine spider venom principles, NSTX-3 and JSTX-3 are described.