113978-98-6

Basic information

• Product Name: dibenzyl-2,4-dihydroxyphenylacetic acid N-hydroxysuccinimide ester
• Synonyms: dibenzyl-2,4-dihydroxyphenylacetic acid N-hydroxysuccinimide ester
• CAS NO: 113978-98-6
• Molecular Weight: 445.472
• Mol File: 113978-98-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: dibenzyl-2,4-dihydroxyphenylacetic acid N-hydroxysuccinimide ester(CAS DataBase Reference)
• NIST Chemistry Reference: dibenzyl-2,4-dihydroxyphenylacetic acid N-hydroxysuccinimide ester(113978-98-6)
• EPA Substance Registry System: dibenzyl-2,4-dihydroxyphenylacetic acid N-hydroxysuccinimide ester(113978-98-6)

Safety Data

• Hazardous Substances Data: 113978-98-6(Hazardous Substances Data)

Upstream product

• 6066-82-6 1-hydroxy-pyrrolidine-2,5-dione 
• 121903-72-8 1-(2,4-Bis-benzyloxy-phenyl)-2-diazo-ethanone 
• 85593-77-7 2,4-bis(benzyloxy)benzoic acid 
• 121903-70-6 benzyl 2,4-bis(benzyloxy)benzoate 
• 100-39-0 benzyl bromide 
• 89-86-1 4-hydroxysalicylic acid 
• 121903-71-7 2,4-bis(benzyloxy)benzoyl chloride 
• 151255-80-0 2,4-dibenzyloxyphenylacetic acid methyl ester 
• 22877-01-6 2,4-bis(benzyloxy)acetophenone 
• 89-84-9 2',4'-dihydroxy-4-acetophenone 
• 66056-40-4 2-(2,4-bis(benzyloxy)phenyl)acetic acid 

Downstream Products

• 113953-98-3 2,4-dibenzyloxyphenylacetyl-L-Asn->Cad<-Pua(Z)-Troc 
• 345898-30-8 4,8-bis(benzyloxycarbonyl)-N¹²-{N^α-[2,4-bis(benzyloxy)phenylacetyl]asparaginyl}-N¹-(2,2,2-trichloroethoxycarbonyl)-4,8-diaza-1,12-dodecanediamine 
• 113954-15-7 (S)-N¹-(5-Amino-pentyl)-2-[2-(2,4-bis-benzyloxy-phenyl)-acetylamino]-succinamide 
• 105029-41-2 Argiotoxin 636 
• 174007-70-6 C₇₅H₈₈N₁₀O₁₄ 
• 172992-23-3 (S)-2-[2-(2,4-Bis-benzyloxy-phenyl)-acetylamino]-N¹-(5-oxo-pentyl)-succinamide 
• 121903-84-2 2,4-dibenzyloxyphenylacetyl-L-Asn->Cad<-Pua(Z)-H 
• 111872-98-1 2,4-dihydroxyphenylacetyl-L-asparagine 
• 113953-99-4 2,4-dibenzyloxyphenylacetyl-L-Asn->Cad<-Pua(Z)<-L-Arg(Z₂)-Z 
• 437718-24-6 {4-[(3-Benzyloxycarbonylamino-propyl)-(2-nitro-benzenesulfonyl)-amino]-butyl}-[2-(5-{(S)-2-[2-(2,4-bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 380635-59-6 4,8-bis(benzyloxycarbonyl)-N¹-[N^α,N^ε-bis(benzyloxycarbonyl)-L-lysyl]-N¹²-{N^α-[2,4-bis(benzyloxy)phenylacetyl]-L-asparaginyl}-4,8-diaza-1,12-dodecanediamine 
• 186370-91-2 N-(7-azido-N-Cbz-4-azaheptanoyl)-N'-(2,4-dibenzoyloxyphenylacetyl-D-asparaginyl)-1,5-pentanediamine 
• 177906-37-5 (3-Azido-propyl)-[2-(5-{(S)-2-[2-(2,4-bis-benzyloxy-phenyl)-acetylamino]-3-carbamoyl-propionylamino}-pentylcarbamoyl)-ethyl]-carbamic acid benzyl ester 
• 174007-67-1 (S)-2-[2-(2,4-Bis-benzyloxy-phenyl)-acetylamino]-N¹-(5-hydroxy-pentyl)-succinamide 

Relevant articles and documents

Practical, convergent total synthesis of polyamine amide spider toxin NSTX-3

A practical, total synthesis of polyamine amide spider toxin NSTX-3, a potent glutamate receptor antagonist with potential as a neuroprotective agent, is reported. The unsymmetrical polyamine moiety was built by a conjugate addition to afford putreanine and regioselective acylation of L-asparaginyl-cadaverine.

Total Synthesis of Polyamine Amide Spider Toxin Argiotoxin-636 by a Practical Reductive Alkylation Strategy

Reductive alkylation is a practical strategy for a total synthesis of spider toxin argiotoxin-636, a polyamine amide which is selective glutamate receptor antagonist and may have potential as a neuroprotective agent.Central to this synthesis are a Swern o

Total synthesis of nstx-3, spider toxin of Nephila maculata

A spider toxin NSTX-3 obtained from the venom of Papua New Guinean spider, Nephila maculata was synthesized in order to confirm its proposed structure and to supply the sample for the biological tests. The structure of NSTX-3 is now established as 2,4-dihydroxyphenylacetyl-L-Asn→Cad←Pua←L-Arg, where Cad stands for cadaverine and Pua for putreanine.