1257660-75-5Relevant academic research and scientific papers
Regioselective Intermolecular Diamination and Aminooxygenation of Alkenes with Saccharin
Martínez, Claudio,Pérez, Edwin G.,Iglesias, álvaro,Escudero-Adán, Eduardo C.,Mu?iz, Kilian
, p. 2998 - 3001 (2016)
Palladium catalysis enables the regioselective difunctionalization of alkenes using saccharin as the nitrogen source in the initial step of aminopalladation. Depending on the reaction conditions, diamination or aminooxygenation pathways can be accessed using hypervalent iodine reagents as the terminal oxidants. The aminooxygenation of allylic ethers originates from an unprecedented ambident behavior of saccharin. The participating palladium catalysts contain a palladium-saccharide unit. Two representative complexes of this type could be isolated and characterized.
PROCESS FOR THE PREPARATION OF 1,2-DIAMINES BY INTERMOLECULAR TRANSFER OF TWO NITROGEN GROUPS ONTO ALKENES AND INTERMEDIATES THEREOF
-
Page/Page column 23-24; 17, (2012/04/04)
A new process for the diamination of alkenes is provided, as well as the new compounds prepared thereof. A process for the preparation of the primary amines obtained from the diaminated alkenes of the provided preparation process is also provided.
An intermolecular palladium-catalyzed diamination of unactivated alkenes
Iglesias, Alvaro,Perez, Edwin G.,Muniz, Kilian
supporting information; experimental part, p. 8109 - 8111 (2011/02/23)
Adding 2Ns: Palladium catalysis introduces two nitrogen groups in a new regio and chemoselective diamination of non-activated alkenes that proceeds under entirely intermolecular reaction control. This palladium-catalyzed reaction employs commercial nitrogen sources in combination with a hypervalent iodo(III) reagent as oxidant (see scheme; Tos=toluenesulfonyl).
