1258076-55-9Relevant articles and documents
Amplification of the inhibitory activity and reversal of the selectivity of miglitol by C(2′)-Monofluorination
Prell, Erik,Korb, Claudia,Kluge, Ralph,Strohl, Dieter,Csuk, Rene
, p. 583 - 589 (2011/06/22)
Selective monofluorination of the α-glycosidase inhibitor and antidiabetic agent miglitol at positions C(2′) or C(6) creates competitive inhibitors of glycosidases. Introducing a fluorine substituent at position C(6) results in a reduced binding to the en