1258076-58-2

Upstream product

• 1194233-02-7 (R)-4,6-O-benzylidene-N-(2-hydroxyethyl)-1,5-dideoxy-1,5-imino-D-glucitol 
• 1194233-03-8 (R)-4,6-O-benzylidene-N-(2-triphenylmethyloxyethyl)-1,5-dideoxy-1,5-imino-D-glucitol 
• 1258076-55-9 2,3-di-O-acetyl-4,6-O-benzylidene-1,5-dideoxy-N-(2-triphenylmethyloxyethyl)-1,5-imino-D-glucitol 
• 1258076-57-1 2,3-di-O-acetyl-4,6-O-benzylidene-1,5-dideoxy-N-(2-hydroxyethyl)-1,5-imino-D-glucitol 
• 100-52-7 benzaldehyde 
• 72432-03-2 migitol 

Relevant academic research and scientific papers

Amplification of the inhibitory activity and reversal of the selectivity of miglitol by C(2′)-Monofluorination

Selective monofluorination of the α-glycosidase inhibitor and antidiabetic agent miglitol at positions C(2′) or C(6) creates competitive inhibitors of glycosidases. Introducing a fluorine substituent at position C(6) results in a reduced binding to the en