1258209-15-2

Basic information

• Product Name: ethyl 2-oxo-6-(5-oxo-2,5-dihydrofuran-2-yl)cyclohexanecarboxylate
• Synonyms: ethyl 2-oxo-6-(5-oxo-2,5-dihydrofuran-2-yl)cyclohexanecarboxylate
• CAS NO: 1258209-15-2
• Molecular Weight: 252.267
• Mol File: 1258209-15-2.mol

Chemical Properties

• CAS DataBase Reference: ethyl 2-oxo-6-(5-oxo-2,5-dihydrofuran-2-yl)cyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-oxo-6-(5-oxo-2,5-dihydrofuran-2-yl)cyclohexanecarboxylate(1258209-15-2)
• EPA Substance Registry System: ethyl 2-oxo-6-(5-oxo-2,5-dihydrofuran-2-yl)cyclohexanecarboxylate(1258209-15-2)

Safety Data

• Hazardous Substances Data: 1258209-15-2(Hazardous Substances Data)

Upstream product

• 61550-02-5 (furan-2-yloxy)-trimethylsilane 
• 57205-09-1 ethyl 6-oxocyclohex-1-enecarboxylate 

Downstream Products

• 1425314-25-5 (1S,6S)-ethyl 1-allyl-2-oxo-6-((R)-5-oxo-2,5-dihydrofuran-2-yl)cyclohexanecarboxylate 
• 1425314-46-0 (1R,6S)-ethyl 1-allyl-2-oxo-6-((R)-5-oxo-2,5-dihydrofuran-2-yl)cyclohexanecarboxylate 
• 1425314-23-3 (1S,6S)-ethyl 1-methyl-2-oxo-6-((R)-5-oxo-2,5-dihydrofuran-2-yl)cyclohexanecarboxylate 
• 1425314-21-1 (S)-2-(ethoxycarbonyl)-3-((R)-5-oxo-2,5-dihydrofuran-2-yl)cyclohex-1-en-1-yl 4-nitrobenzoate 
• 1425313-67-2 (S)-ethyl 2-((diphenoxyphosphoryl)oxy)-6-((R)-5-oxo-2,5-dihydrofuran-2-yl)cyclohex-1-enecarboxylate 
• 1425314-27-7 (R)-5-((S)-3-oxocyclohexyl)dihydrofuran-2(3H)-one 

Relevant articles and documents

Vinylogous Mukaiyania-Michael Reactions between 2-SiLyIoxyfurans and cyclic enones or unsaturated oxo esters

Lewis acid catalyzed vinylogous Mukaiyama-Michael (VMM) reactions between 2-(trialkylsilyloxy)furans 1 and α, β-unsaturated cyclic enones 2 or oxo esters 4 have been investigated. Both substrates proved to be useful Michael acceptors in the title reaction, giving the butenolides 3 and 5 in good yields. A comparative study between the α,β-unsaturated cyclic enones 2 and the oxo esters 4 as Michael acceptors showed better diasterecontrol with the latter class of compounds. In both series, crystal structures of the major isomers revealed anti relationships of newly formed stereogenic centers. From these data, two types of transition states could be proposed: an open TS with antiperiplanar orientation or a Diels-Alder-like TS with exo approach.