1258237-27-2Relevant academic research and scientific papers
Asymmetric [3 + 2] Cycloaddition of Methyleneindolinones with N,N′-Cyclic Azomethine Imines Catalyzed by a N,N′-Dioxide-Mg(OTf)2 Complex
Yin, Chengkai,Lin, Lili,Zhang, Dong,Feng, Juhua,Liu, Xiaohua,Feng, Xiaoming
, p. 9691 - 9699 (2015)
A highly efficient chiral N,N′-dioxide-Mg(OTf)2 catalyst system has been developed for the asymmetric 1,3-dipolar cycloaddition between methyleneindolinones and N,N′-cyclic azomethine imines. The desired pyrazolidine products with contiguous qu
Bronsted acid or lewis acid catalyzed [3+3] cycloaddition of azomethine imines with N-benzyl azomethine ylide: A facile access to bicyclic N-heterocycles
Li, Shuo-Ning,Yu, Bin,Liu, Jia,Li, Hong-Lian,Na, Risong
supporting information, p. 282 - 286 (2016/01/20)
1,3-Dipolar cycloaddition reactions are one of the most important methods to obtain diverse heterocycles with novel skeletons. We herein report the Bronsted acid or Lewis acid catalyzed [3+3] cycloaddition of azomethine imines with nonstabilized azomethine ylide generated in situ from an N-benzyl precursor, providing a clean and facile access to diverse bicyclic N-heterocycles in moderate to good yields for further biological testing. Also, the protocol developed achieved the formation of C-C and C-N bonds simultaneously in a single step.
