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ethyl (R)-2-hydroxy-4-phenyl-2-(trifluoromethyl)but-3-ynoate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1258456-56-2

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1258456-56-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1258456-56-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,8,4,5 and 6 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1258456-56:
(9*1)+(8*2)+(7*5)+(6*8)+(5*4)+(4*5)+(3*6)+(2*5)+(1*6)=182
182 % 10 = 2
So 1258456-56-2 is a valid CAS Registry Number.

1258456-56-2Relevant academic research and scientific papers

Modulation of the coordination geometries of NCN and NCNC Rh complexes for ambidextrous chiral catalysts

Ito, Jun-Ichi,Ishihara, Takahiro,Fukuoka, Takaki,Binti Mat Napi, Siti Rokiah,Kameo, Hajime,Nishiyama, Hisao

, p. 12765 - 12768 (2019)

A chirality switch between novel NCN pincer Rh complexes and a related double cyclometalated NCNC Rh complex containing secondary amino groups is described. Their catalytic abilities were determined in asymmetric alkynylation of ethyl trifluoropyruvate, a

Octahedral Ruthenium Complex with Exclusive Metal-Centered Chirality for Highly Effective Asymmetric Catalysis

Zheng, Yu,Tan, Yuqi,Harms, Klaus,Marsch, Michael,Riedel, Radostan,Zhang, Lilu,Meggers, Eric

supporting information, p. 4322 - 4325 (2017/04/06)

A novel ruthenium catalyst is introduced which contains solely achiral ligands and acquires its chirality entirely from octahedral centrochirality. The configurationally stable catalyst is demonstrated to catalyze the alkynylation of trifluoromethyl ketones with very high enantioselectivity (up to >99% ee) at low catalyst loadings (down to 0.2 mol%).

Chiral NCN pincer rhodium(III) complexes with bis(imidazolinyl)phenyl ligands: Synthesis and enantioselective catalytic alkynylation of trifluoropyruvates with terminal alkynes

Wang, Tao,Niu, Jun-Long,Liu, Shuang-Liang,Huang, Juan-Juan,Gong, Jun-Fang,Song, Mao-Ping

, p. 927 - 937 (2013/05/08)

A series of new chiral C2-symmetrical NCN pincer rhodium(III) complexes with bis(imidazolinyl)phenyl ligands have been conveniently synthesized from easily available materials. The complexes were subsequently applied in the enantioselective add

C1-symmetric Rh/Phebox-catalyzed asymmetric alkynylation of α-ketoesters

Ohshima, Takashi,Kawabata, Takahito,Takeuchi, Yosuke,Kakinuma, Takahiro,Iwasaki, Takanori,Yonezawa, Takayuki,Murakami, Hajime,Nishiyama, Hisao,Mashima, Kazushi

supporting information; experimental part, p. 6296 - 6300 (2011/09/13)

Thinking outside the box: A newly developed C1-symmetric Rh/Phebox complex efficiently catalyzed the asymmetric alkynylation of α-ketoester 1 with various aryl and alkyl substituted terminal alkynes to provide the corresponding chiral tertiary propargylic alcohols with up to 99 % ee (see scheme; TMS=trimethylsilyl). Copyright

Highly enantioselective alkynylation of trifluoropyruvate with alkynylsilanes catalyzed by the BINAP - Pd complex: Access to -trifluoromethyl-substituted tertiary alcohols

Aikawa, Kohsuke,Hioki, Yuta,Mikami, Koichi

supporting information; experimental part, p. 5716 - 5719 (2011/03/23)

A highly enantioselective alkynylation catalyzed by the dicationic (S)-BINAP - Pd complex with a variety of alkynylsilanes and trifluoropyruvate is described. The catalytic reaction is applicable to highly enantioselective addition of polyyne to trifluoro

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