1259020-46-6Relevant articles and documents
Discovery of GCC5694A: A potent and selective sodium glucose co-transporter 2 inhibitor for the treatment of type 2 diabetes
Kong, Young Kyu,Song, Kwang-Seop,Jung, Myung Eun,Kang, Misuk,Kim, Hyeon Jung,Kim, Min Ju
supporting information, (2021/12/02)
Sodium-dependent glucose co-transporter 2 (SGLT2) has emerged as a promising drug target for the treatment of type 2 diabetes, and recently, several SGLT2 inhibitors have been approved for clinical use. A series of molecules with a C-aryl glucoside scaffo
FURANE DERIVATIVES AS INHIBITORS OF ATAD2
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Paragraph 90; 91, (2017/07/19)
The invention relates to fur an e derivatives of formula (I) as inhibitors of ATAD2, a process for their preparation and use thereof.
Novel macrocyclic C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents
Kim, Min Ju,Lee, Suk Ho,Park, So Ok,Kang, Hyunku,Lee, Jun Sung,Lee, Ki Nam,Jung, Myung Eun,Kim, Jeongmin,Lee, Jinhwa
experimental part, p. 5468 - 5479 (2011/10/30)
Novel macrocyclic C-aryl glucoside SGLT2 inhibitors were designed and synthesized. Two different synthetic routes of macrocyclization were adopted to prepare novel ansa SGLT2 inhibitors. Among the compounds tested, [1,7]dioxacyclopentadecine macrocycles p