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1259379-37-7

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1259379-37-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1259379-37-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,9,3,7 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1259379-37:
(9*1)+(8*2)+(7*5)+(6*9)+(5*3)+(4*7)+(3*9)+(2*3)+(1*7)=197
197 % 10 = 7
So 1259379-37-7 is a valid CAS Registry Number.

1259379-37-7Downstream Products

1259379-37-7Relevant articles and documents

Discovery of pyrrolo-benzo-1,4-diazines as potent Nav1.7 sodium channel blockers

Ho, Ginny D.,Tulshian, Deen,Bercovici, Ana,Tan, Zheng,Hanisak, Jennifer,Brumfield, Stephanie,Matasi, Julius,Heap, Charles R.,Earley, William G.,Courneya, Brandy,Jason Herr,Zhou, Xiaoping,Bridal, Terry,Rindgen, Diane,Sorota, Steve,Yang, Shu-Wei

, p. 4110 - 4113 (2014/11/07)

A series of pyrrolo-benzo-1,4-diazine analogs have been synthesized and displayed potent Nav1.7 inhibitory activity and moderate selectivity over Nav1.5. The syntheses, structure-activity relationships, and selected pharmacokinetic data of these analogs are described. Compound 41 displayed anti-nociceptive efficacy in the rat CFA pain model at 100 mpk oral dosing.

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