1259389-22-4

Basic information

• Product Name: 2-(4-(4-butyl-1H-1,2,3-triazol-1-yl)phenyl)-3-p-tolylimidazo-[1,2-a]pyrimidine
• Synonyms: 2-(4-(4-butyl-1H-1,2,3-triazol-1-yl)phenyl)-3-p-tolylimidazo-[1,2-a]pyrimidine
• CAS NO: 1259389-22-4
• Molecular Weight: 408.506
• Mol File: 1259389-22-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-(4-butyl-1H-1,2,3-triazol-1-yl)phenyl)-3-p-tolylimidazo-[1,2-a]pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(4-butyl-1H-1,2,3-triazol-1-yl)phenyl)-3-p-tolylimidazo-[1,2-a]pyrimidine(1259389-22-4)
• EPA Substance Registry System: 2-(4-(4-butyl-1H-1,2,3-triazol-1-yl)phenyl)-3-p-tolylimidazo-[1,2-a]pyrimidine(1259389-22-4)

Safety Data

• Hazardous Substances Data: 1259389-22-4(Hazardous Substances Data)

Upstream product

• 31827-94-8 2-bromo-1-(4-iodophenyl)ethanone 
• 118001-69-7 2-(4-iodophenyl)imidazo[1,2-a]pyrimidine 
• 13329-40-3 4-Iodoacetophenone 
• 106-38-7 para-bromotoluene 
• 1259389-18-8 2-(4-(4-butyl-1H-1,2,3-triazole)phenyl)imidazo[1,2-a]-pyrimidine 

Relevant articles and documents

Predictable and site-selective functionalization of poly(hetero)arene compounds by palladium catalysis

The challenge of achieving selective and predictable functionalizations at C-H bonds with complex poly(hetero)aromatic substrates was addressed by two different approaches. Site-selectivity can be obtained by applying various reaction conditions that are (hetero)arene specific to substrates that contain indoles, pyridine N-oxide, and polyfluorinated benzenes. An experimental classification of electron-rich heteroarenes based on their reactivity toward palladium-catalyzed C-Hfunctionalization was established, the result of which correlated well with the order of reactivity predicted by the DFT-calculated concerted metalation-deprotonation (CMD) pathway. Model substrates containing two reactive heteroarenes were then reacted under general reaction conditions to demonstrate the applicability this reactivity chart in predicting the regioselectivity of the palladium-catalyzed direct arylation and benzylation reactions.