1260000-13-2Relevant academic research and scientific papers
Copper-assisted preparation of pyridinyl sulfonate esters from hydroxypyridines and sodium sulfinates
Fan, Qiangwen,Le, Zhang-Gao,Li, Qian,Liu, Yishuai,Xie, Zongbo,Yang, Liu,Zhu, Haibo
, p. 2736 - 2740 (2022/02/09)
An efficient and powerful copper-assisted method for the effective conversion of a broad range of hydroxypyridines and sodium sulfinates into their corresponding pyridinyl tosylates was developed. Key features of this base- and ligand-free protocol include using the cheap and readily available CuBr2 as a medium and the use of sodium sulfinates as formal sulfonylation reagents. A variety of functional pyridinyl tosylates could be formed with good yields, which can easily be converted into C-C and C-N bond-containing compounds. This journal is
