1260237-23-7Relevant academic research and scientific papers
Water-mediated strecker reaction: An efficient and environmentally friendly approach for the synthesis of α-aminonitriles via a three-component condensation
Ramesh, Samikannu,Sivakumar, Kulanthaivel,Panja, Chiradeep,Arunachalam, Pirama Nayagam,Lalitha, Appaswami
experimental part, p. 3544 - 3551 (2011/01/12)
The synthesis of α-aminonitriles by a direct three component Strecker reaction has been achieved in water, which is found to be an inexpensive, non-toxic and eco-friendly reaction medium for the nucleophilic addition. This protocol is effective to a wide variety of substrates with different functional groups and does not require the use any other catalyst. Copyright Taylor & Francis Group, LLC.
