1261061-25-9

Basic information

• Product Name: (S)-2-benzyl-7-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one
• Synonyms: (S)-2-benzyl-7-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one
• CAS NO: 1261061-25-9
• Molecular Weight: 253.304
• Mol File: 1261061-25-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-2-benzyl-7-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-benzyl-7-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one(1261061-25-9)
• EPA Substance Registry System: (S)-2-benzyl-7-methyl-1,4-dihydropyrido[2,3-b]pyrazin-3(2H)-one(1261061-25-9)

Safety Data

• Hazardous Substances Data: 1261061-25-9(Hazardous Substances Data)

Upstream product

• 63-91-2 L-phenylalanine 
• 17282-00-7 3-bromo-5-methylpyridin-2-amine 

Relevant articles and documents

Synthesis of Kappa Opioid Antagonists Based on Pyrrolo[1,2-α]quinoxalinones Using an N-Arylation/Condensation/Oxidation Reaction Sequence

The quinoxaline and quinoxalinone family of nitrogen heterocycles is present in molecules of therapeutic relevance for diverse applications ranging from infectious diseases to neuroscience targets. Here, we describe a general synthetic sequence to afford pyrrolo[1,2-α]quinoxalinones from commercially available starting materials and their use in preparing potential kappa opioid receptor antagonists. The biological data obtained from the latter set of compounds is briefly presented and discussed.

A general and practical access to chiral quinoxalinones with low copper-catalyst loading

A general, straightforward, and practical access to multi-substituted chiral quinoxalin-2-ones has been achieved based on the copper(I) chloride-dimethylethylenediamine (DMEDA) catalyst system. With the use of 1 mol% copper(I) chloride, structurally diverse quinoxalin-2-ones were generated with high optical purity from readily available starting materials, 2-haloanilines and α-amino acids, in a one-pot manner.