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126111-14-6

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126111-14-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 126111-14-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,6,1,1 and 1 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 126111-14:
(8*1)+(7*2)+(6*6)+(5*1)+(4*1)+(3*1)+(2*1)+(1*4)=76
76 % 10 = 6
So 126111-14-6 is a valid CAS Registry Number.

126111-14-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl (2S)-4,4-difluoropyrrolidine-2-carboxylate,hydrochloride

1.2 Other means of identification

Product number -
Other names (S)-methyl 4,4-difluoropyrrolidine-2-carboxylate hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:126111-14-6 SDS

126111-14-6Relevant articles and documents

Solid dispersions containing an apoptosis-inducing agent

-

Page/Page column 121, (2019/03/15)

A pro-apoptotic solid dispersion comprises, in essentially non-crystalline form, a Bcl-2 family protein inhibitory compound of Formula I as defined herein, dispersed in a solid matrix that comprises (a) a pharmaceutically acceptable water-soluble polymeric carrier and (b) a pharmaceutically acceptable surfactant. A process for preparing such a solid dispersion comprises dissolving the compound, the polymeric carrier and the surfactant in a suitable solvent, and removing the solvent to provide a solid matrix comprising the polymeric carrier and the surfactant and having the compound dispersed in essentially non-crystalline form therein. The solid dispersion is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.

SPIRO COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS

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, (2015/11/09)

Disclosed are spiro compounds of formula (I), or stereomers, geometric isomers, tautomers, nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs thereof. The compounds can be used to treat hepatitis C virus (HCV) infection or hepatitis C disease. Furthermore disclosed are pharmaceutical compositions containing the compounds and the method of using the compounds or pharmaceutical compositions in the treatment of HCV infection or hepatitis C disease.

Remarkable enhancement in the DNA-binding ability of C2-fluoro substituted pyrrolo[2,1-c][1,4]benzodiazepines and their anticancer potential

Kamal, Ahmed,Rajender,Reddy, D. Rajasekhar,Reddy, M. Kashi,Balakishan,Shaik, T. Basha,Chourasia, Mukesh,Sastry, G. Narahari

experimental part, p. 1557 - 1572 (2009/08/15)

C2-Fluoro substituted DC-81, and its dimers that comprise of two C2-fluoro substituted DC-81 subunits tethered to their C8-position through simple alkane spacers as well as piperazine moiety side-armed with symmetrical alkyloxy spacers have been designed

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