126116-23-2Relevant academic research and scientific papers
Eco-friendly Oxidative Iodination of Various Arenes with a Urea-Hydrogen Peroxide Adduct (UHP) as the Oxidant
Lulinski, Piotr,Kryska, Anna,Sosnowski, Maciej,Skulski, Lech
, p. 441 - 445 (2004)
Three easy eco-friendly laboratory procedures are presented for the oxidative iodination of various activated and deactivated arenes with molecular iodine, in the presence of UHP (percarbamide), a stable, strongly H-bonded, solid urea-hydrogen peroxide adduct as the oxidant.
IrIII-Catalyzed Selective ortho-Monoiodination of Benzoic Acids with Unbiased C?H Bonds
Weis, Erik,Johansson, Magnus J.,Martín-Matute, Belén
supporting information, p. 10185 - 10190 (2020/07/31)
An iridium-catalyzed selective ortho-monoiodination of benzoic acids with two equivalent C?H bonds is presented. A wide range of electron-rich and electron-poor substrates undergo the reaction under mild conditions, with >20:1 mono/di selectivity. Importantly, the C?H iodination occurs selectively ortho to the carboxylic acid moiety in substrates bearing competing coordinating directing groups. The reaction is performed at room temperature and no inert atmosphere or exclusion of moisture is required. Mechanistic investigations revealed a substrate-dependent reversible C?H activation/protodemetalation step, a substrate-dependent turnover-limiting step, and the crucial role of the AgI additive in the deactivation of the iodination product towards further reaction.
Kinetics of Iodination of Some Substituted Benzoic Acids by N-Iodosuccinimide
Radhakrishnamurti, P. S.,Panda, B. K.
, p. 770 - 773 (2007/10/02)
Iodination of o-amino-, p-amino-, o-hydroxy-, p-hydroxy, o-acetylamino-, p-acetylamino-, o-methoxy- and p-methoxy-benzoic acids by N-iodosuccinimide (NIS) in mixtures of acetic acid and perchloric acid follows first order kinetics with respect to the halo
