126149-60-8

Upstream product

• 598-21-0 2-Bromoacetyl bromide 
• 126149-53-9 7-(2-fluorobenzoyl)-indoline 
• 394-47-8 2-fluorobenzonitrile 
• 496-15-1 1-indoline 

Downstream Products

• 129042-14-4 1-(2-fluorophenyl)-4-oxo-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-2-oxide 
• 129041-82-3 (3S)-3-(2-aminocinnamoyl)amino-1-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 129100-97-6 (3RS)-1-(2-fluorophenyl)-3-(2-nitrocinnamoyl)amino-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 129041-94-7 (3RS)-3-(2-aminocinnamoyl)amino-1-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 129100-96-5 (3S)-3-amino-5-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 126149-63-1 (3RS)-3-amino-1-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 167644-99-7 (3RS)-3-acetoxy-1-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>-benzodiazepin-4(3H)-one 

Relevant academic research and scientific papers

Studies on a novel, potent and orally effective cholecystokinin A antagonist, FK-480. Synthesis and structure-activity relationships of FK-480 and related compounds

We prepared various novel tricyclic 1,4-benzodiazepine derivatives as cholecystokinin (CCK) A antagonists, which were evaluated preliminarily for inhibition of 125I-CCK-8 binding to rat pancreatic membranes in vitro and inhibiting effect on CCK

Benzodiazepines, process and intermediates for the preparation thereof and their application in therapy

Benzodiazepines of formula STR1 in which R1 is H of halogen, R2 is H or halogen, Ar is indolyl, phenyl, naphthyl, indolyl monosubstituted with a halogen or with a methoxy or phenyl mono-, di- or trisubstituted with a halogen or with