167644-99-7

Upstream product

• 126149-60-8 1-(bromoacetyl)-7-(2-Fluorobenzoyl)indoline 
• 126149-53-9 7-(2-fluorobenzoyl)-indoline 
• 394-47-8 2-fluorobenzonitrile 
• 496-15-1 1-indoline 
• 108-24-7 acetic anhydride 
• 129042-14-4 1-(2-fluorophenyl)-4-oxo-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-2-oxide 

Downstream Products

• 129041-82-3 (3S)-3-(2-aminocinnamoyl)amino-1-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 129100-97-6 (3RS)-1-(2-fluorophenyl)-3-(2-nitrocinnamoyl)amino-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 129041-94-7 (3RS)-3-(2-aminocinnamoyl)amino-1-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 129100-96-5 (3S)-3-amino-5-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 126149-63-1 (3RS)-3-amino-1-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>benzodiazepin-4(3H)-one 
• 150408-73-4 (3S)-1-(2-fluorophenyl)-3,4,6,7-tetrahydro-3-(2-indolylcarbonylamino)-4-oxopyrrolo[3,2,1-jk][1,4]benzodiazepine 
• 167645-00-3 (3RS)-3-hydroxyl-1-(2-fluorophenyl)-3,4,6,7-tetrahydropyrrolo<3,2,1-jk><1,4>-benzodiazepin-4(3H)-one 

Relevant academic research and scientific papers

Studies on a novel, potent and orally effective cholecystokinin A antagonist, FK-480. Synthesis and structure-activity relationships of FK-480 and related compounds

We prepared various novel tricyclic 1,4-benzodiazepine derivatives as cholecystokinin (CCK) A antagonists, which were evaluated preliminarily for inhibition of 125I-CCK-8 binding to rat pancreatic membranes in vitro and inhibiting effect on CCK