126187-01-7

Usage

Molecular Structure

Cyclobutanedimethanol backbone with a purine derivative attached
The compound consists of a four-carbon ring (cyclobutane) with two hydroxymethyl groups (-CH2OH) and a purine derivative attached to the third carbon.

Chirality

One stereocenter at the first carbon atom, two at the second and third carbon atoms
The compound is chiral, meaning it has non-superimposable mirror images. It has three stereocenters, contributing to its stereoisomeric diversity.

Stereochemistry

(1S,2R,3R)-
The stereochemistry of the compound is defined by the (1S,2R,3R)notation, which specifies the absolute configuration of the stereocenters.

Purine Derivative

6-amino-9H-purin-9-yl
The purine derivative is an important component of the compound, as it is a part of DNA and RNA and is involved in various physiological processes.

Potential Biological Activity

Associated with DNA and RNA, various physiological processes
Due to the presence of the purine derivative, the compound may have potential biological activity and could be relevant to pharmaceuticals or biotechnology.

Research and Applications

Interesting target for further research, potential applications in pharmaceuticals or biotechnology
The compound's unique structure and potential biological significance make it a promising candidate for further research and possible applications in the fields of medicine and biotechnology.

Upstream product

• 14036-06-7 diethoxymethyl acetate 
• 5413-85-4 5-amino-4,6-dichloropyridimine 
• 130368-92-2 (1β,2α,3β)-2,3-bis(tert-butyldimethylsiloxymethyl)cyclobutylamine 
• 136738-10-8 [(1S,2S,4R)-2-Amino-4-(tert-butyl-dimethyl-silanyloxymethyl)-cyclobutyl]-methanol 
• 122-51-0 orthoformic acid triethyl ester 
• 124770-84-9 C₂₅H₃₅N₅O₄ 
• 66224-66-6 adenine 
• 10374-07-9 3-oxabicyclo<3.2.0>hept-6-ene-2,4-dione 
• 124770-79-2 C₂₄H₂₈O₆ 
• 132294-20-3 (1'S,2'S,3'R)-9-[2',3'-bis(benzoyloxymethyl)cyclobutyl]adenine 
• 124770-84-9 C₂₅H₃₅N₅O₄ 
• 124794-61-2 C₂₅H₃₃ClN₄O₄ 
• 124770-81-6 trans-2,3-bis-(benzoyloxymethyl)cyclobutanone oxime 
• 124770-80-5 trans-2,3-bis(benzoyloxymethyl)cyclobutanone 

Relevant academic research and scientific papers

Synthesis and hybridization property of oligonucleotides containing carbocyclic oxetanocins

Oligonucleotides containing enantiomeric carbocyclic oxetanocins possessing adenine, thymine, guanine and cytosine were synthesized from an optically active cyclobutane derivative. Their hybridization properties with the complementary oligonucleotides were studied using melting point method, CD spectroscopy, and mixing curve method (Job plots). The artificial nucleotides possessing adenine, guanine and cytosine bases show tendency to form complexes more strongly with ribonucleotide than deoxyribonucleotide. These complexes are triplexes consisting of purine and pyrimidine in 1:2 ratio. Such triplex formation is observed both under high (1 M NaCl) and low salt conditions (0.1 M NaCl). (C) 2000 Elsevier Science Ltd.

Highly regio- and enantio-selective deacylation of carbocyclic 3',5'- di-O-acyloxetanocins by lipases

Carbocyclic (-)-3',5'-di-O-acyloxetanocin A and T were hydrolysed by lipase MY to give the corresponding carbocyclic (-)-3'-O-acyloxetanocins with high regioselectivity. Carbocyclic (±)-3',5'-di-O-acetyloxetanocin A was deacetylated by lipase MY to form t

Synthesis of a Carboxylic Oxetanocin Using Photocycloaddition

All-cis-3-acetoxycyclobutane-1,2-dicarboxylate 4 was provided from a photochemical endo-cycloadduct between maleic anhydride and vinyl acetate, and 4 was coupled with adenine and reduced with LiAlH4 to give a carboxylic oxetanocin 6.