126202-91-3

Basic information

• Product Name: 2-AMINO-4-(4-FLUOROPHENYL)-6-PHENYLNICOTINONITRILE
• Synonyms: 2-AMINO-4-(4-FLUOROPHENYL)-6-PHENYLNICOTINONITRILE;BUTTPARK 115\40-27
• CAS NO: 126202-91-3
• Molecular Formula: C18H12FN3
• Molecular Weight: 289.31
• Mol File: 126202-91-3.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-AMINO-4-(4-FLUOROPHENYL)-6-PHENYLNICOTINONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-4-(4-FLUOROPHENYL)-6-PHENYLNICOTINONITRILE(126202-91-3)
• EPA Substance Registry System: 2-AMINO-4-(4-FLUOROPHENYL)-6-PHENYLNICOTINONITRILE(126202-91-3)

Safety Data

• Hazardous Substances Data: 126202-91-3(Hazardous Substances Data)

Usage

General Description

2-AMINO-4-(4-FLUOROPHENYL)-6-PHENYLNICOTINONITRILE is a chemical compound with the molecular formula C20H14FN3. It is a derivative of nicotinonitrile, containing an amino group, a fluorophenyl group, and a phenyl group. 2-AMINO-4-(4-FLUOROPHENYL)-6-PHENYLNICOTINONITRILE is commonly used in organic synthesis and medicinal chemistry for the development of pharmaceutical drugs and agrochemicals due to its potential biological activities and pharmacological properties. However, it is important to handle this chemical with caution and follow proper safety protocols when working with it in a laboratory setting.

Upstream product

• 459-57-4 4-fluorobenzaldehyde 
• 100-52-7 benzaldehyde 
• 57-13-6 urea 
• 109-77-3 malononitrile 
• 98-86-2 acetophenone 

Relevant articles and documents

Unveiling the urease like intrinsic catalytic activities of two dinuclear nickel complexes towards thein situsyntheses of aminocyanopyridines

Designing metal complexes as functional models for metalloenzymes remains one of the main targets in synthetic bioinorganic chemistry. Furthermore, the utilization of the product(s) derived from the catalytic reaction for subsequent organic transformation

β-Cyclodextrin: A supramolecular catalyst for metal-free approach towards the synthesis of 2-amino-4,6-diphenylnicotinonitriles and 2,3-dihydroquinazolin-4(1 H)-one

β-Cyclodextrin, a green and widespread supramolecular catalyst, has been explored as a highly proficient promoter for the metal-free one-pot multi-component synthesis of a vast range of highly functionalized bioactive heterocyclic moiety, 2-amino-4,6-diphenylnicotinonitriles and 2,3-dihydroquinazolin-4(1H)-one, from easily available precursor aldehydes. The main endeavor of these protocols is to explore this organic supramolecule in one-pot multi-component synthesis. Absence of metal catalyst or toxic acid and harsh reaction conditions, excellent functional group tolerance, inexpensive, greener and environmentally safe protocol are the key advantages of this work.

Synthesis, cytotoxic assessment, and molecular docking studies of 2,6-diaryl-substituted pyridine and 3,4-dihydropyrimidine-2(1H)-one scaffolds

Cancer is one of the main global health problems. In order to develop novel antitumor agents, we synthesized 3,4-dihydropyrimidine-2(1H)-one (DHPM) and 2,6-diaryl-substituted pyridine derivatives as potential antitumor structures and evaluated their cytot