1262209-98-2Relevant academic research and scientific papers
Metal-free sequential [3 + 2]-dipolar cycloadditions using cyclooctynes and 1,3-dipoles of different reactivity
Sanders, Brian C.,Friscourt, Frederic,Ledin, Petr A.,Mbua, Ngalle Eric,Arumugam, Selvanathan,Guo, Jun,Boltje, Thomas J.,Popik, Vladimir V.,Boons, Geert-Jan
, p. 949 - 957 (2011/04/16)
Although metal-free cycloadditions of cyclooctynes and azides to give stable 1,2,3-triazoles have found wide utility in chemical biology and material sciences, there is an urgent need for faster and more versatile bioorthogonal reactions. We have found th
