1262523-85-2 Usage
Uses
Used in Organic Synthesis:
(2R,4S)-tert-butyl-2-(tert-butoxycarbonylamino)-5-oxo-4-(tosyloxy)-5-(2,4,6-trimethoxybenzylamino)pentanoate is used as a versatile building block for the synthesis of complex organic molecules. Its multiple functional groups allow for a wide range of chemical reactions, making it a valuable component in the creation of new compounds with potential applications in various fields.
Used in Medicinal Chemistry:
(2R,4S)-tert-butyl-2-(tert-butoxycarbonylamino)-5-oxo-4-(tosyloxy)-5-(2,4,6-trimethoxybenzylamino)pentanoate is used as a key intermediate in the development of pharmaceuticals. Its diverse pharmacological activities and potential for creating new molecules with therapeutic applications make it an important compound in the field of medicinal chemistry.
Used in Drug Development:
(2R,4S)-tert-butyl-2-(tert-butoxycarbonylamino)-5-oxo-4-(tosyloxy)-5-(2,4,6-trimethoxybenzylamino)pentanoate is used as a potential drug candidate for the treatment of various diseases. Its complex structure and multiple functional groups allow for the development of new molecules with therapeutic properties, making it a valuable asset in the search for novel treatments.
Used in Pharmaceutical Industry:
(2R,4S)-tert-butyl-2-(tert-butoxycarbonylamino)-5-oxo-4-(tosyloxy)-5-(2,4,6-trimethoxybenzylamino)pentanoate is used as a valuable component in the pharmaceutical industry for the development of new drugs and pharmaceutical intermediates. Its versatility and potential for creating molecules with therapeutic applications make it an important tool in the industry.
Check Digit Verification of cas no
The CAS Registry Mumber 1262523-85-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,5,2 and 3 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1262523-85:
(9*1)+(8*2)+(7*6)+(6*2)+(5*5)+(4*2)+(3*3)+(2*8)+(1*5)=142
142 % 10 = 2
So 1262523-85-2 is a valid CAS Registry Number.
1262523-85-2Relevant articles and documents
Synthesis of optically pure 4-fluoro-glutamines as potential metabolic imaging agents for tumors
Qu, Wenchao,Zha, Zhihao,Ploessl, Karl,Lieberman, Brian P.,Zhu, Lin,Wise, David R.,Thompson, Craig B.,Kung, Hank F.
, p. 1122 - 1133 (2011/04/16)
A versatile synthetic route to prepare all four stereoisomeric 4-fluoro-glutamines was developed by exploiting a Passerini three-component reaction. The skeleton of 4-substituted glutamine derivatives was efficiently constructed. Subsequent four-step reactions, highlighted by a "neutralized" TASF fluorination, provided the desired products with high yields and excellent optical purity. The optically pure fluorine-18 labeled 4-fluoroglutamines were also successfully prepared using either a 18-crown-6/KHCO3 or K[222]/K2CO3 catalysis system. Preliminary cell uptake and inhibition studies using the 9L tumor cells ana SF188BC1-XL tumor cells (a glutamine addicted tumor derived from glioblastoma) provided strong evidence for their potential application in conjunction with positron emission tomography (PET) for in vivo imaging of tumors, which use glutamine as an alternative energy source.