1262675-61-5

Upstream product

• 100-42-5 styrene 
• 2521-89-3 ethyl 2-((4-chlorophenyl)amino)acetate 
• 106-47-8 4-chloro-aniline 
• 924-44-7 glyoxylic acid ethyl ester 
• 536-74-3 phenylacetylene 

Relevant academic research and scientific papers

TBN as a metal-free reagent initiated sp3 C–H functionalization of glycine esters: Synthesis of quinoline-2-carboxylate esters

As a metal-free reagent, tert-butylnitrite (TBN) initiated aerobic sp3 C–H bond oxidation of glycine esters was achieved, providing a series of quinoline-2-carboxylates in good yields. The mechanistic investigation revealed that in the presence

Gold-Oxazoline Complex-Catalyzed Cross-Dehydrogenative Coupling of Glycine Derivatives and Alkenes

A gold-oxazoline complex-catalyzed dehydrogenative Povarov/oxidation tandem reaction for the synthesis of decorated quinolines has been developed from glycine derivatives and alkenes. The reaction performs under mild reaction conditions in the presence of

An economical synthesis of substituted quinoline-2-carboxylates through the potassium persulfate-mediated cross-dehydrogenative coupling of N-aryl glycine derivatives with olefins

A practical and economical K2S2O8-mediated oxidative cross-dehydrogenative coupling of N-aryl glycine derivatives with olefins has been established, affording structurally diverse quinoline-2-carboxylates in good to high e

Visible-Light-Induced Photocatalytic Aerobic Oxidative Csp3-H Functionalization of Glycine Derivatives: Synthesis of Substituted Quinolines

A visible-light induced photocatalytic aerobic oxidative dehydrogenative coupling/aromatization tandem reaction of glycine esters with unactivated alkenes has been accomplished. This visible light-driven protocol has been successfully applied to a broad s

Copper(II) Triflate-Catalyzed Aerobic Oxidative C-H Functionalization of Glycine Derivatives with Olefins and Organoboranes

An economical, and practical copper(II) triflate-catalyzed aerobic oxidative C-H functionalization of glycine derivatives with olefins and organoboranes has been established. The mild reaction has an excellent functional group tolerance, and exhibits a br

Iron-catalyzed oxidative tandem reactions with TEMPO oxoammonium salts: Synthesis of dihydroquinazolines and quinolines

A straightforward iron-catalyzed divergent oxidative tandem synthesis of dihydroquinazolines and quinolines from N-alkylanilines using a TEMPO oxoammonium salt as a mild and nontoxic oxidant has been developed. Fe(OTf) 2 was the Lewis acid cata

Catalytic radical cation salt induced Csp3-H functionalization of glycine derivatives: Synthesis of substituted quinolines

A domino Csp3-H functionalization of glycine derivatives was achieved under catalytic radical cation salt induced conditions, producing a series of quinolines. The proposed mechanism shows that a peroxyl radical cation, which is generated by th

TEMPO oxoammonium salt-mediated dehydrogenative Povarov/oxidation tandem reaction of N-alkyl anilines

The synthesis of a variety of substituted quinolines from N-alkyl anilines by a one-pot dehydrogenative Povarov/oxidation tandem reaction with mono- and 1,2-disubstituted aryl and alkyl olefins was developed. A simple protocol using cheap and benign iron(

Molecular iodine-catalyzed and air-mediated tandem synthesis of quinolines via three-component reaction of amines, aldehydes, and alkynes

A one-pot synthesis of quinolines via molecular iodine-catalyzed and air-mediated tandem condensation/imino-Diels-Alder/isomerization/oxidation of simple readily available amines, aldehydes, and alkynes has been developed. This methodology was extended to synthesize quinazolines from two molecules of amines and two molecules of glyoxalates.