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(E)‐1‐(2,4‐dimethoxyphenyl)‐3‐(3,4,5‐trimethoxyphenyl)prop‐2‐en‐1‐one, also known as Calebin-A, is a natural compound derived from turmeric. It belongs to the curcuminoid family, which are recognized for their antioxidant and anti-inflammatory properties. Calebin-A has been investigated for its potential health benefits, including anti-cancer, anti-microbial, and anti-diabetic properties. Additionally, it has demonstrated neuroprotective effects, suggesting its potential use as a therapeutic agent for neurological disorders. However, further research is necessary to fully comprehend the mechanisms and possible applications of Calebin-A.

1262675-76-2

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1262675-76-2 Usage

Uses

Used in Pharmaceutical Applications:
Calebin-A is used as a therapeutic agent for various health conditions due to its anti-cancer, anti-microbial, and anti-diabetic properties. Its antioxidant and anti-inflammatory characteristics contribute to its potential in treating a range of diseases and promoting overall health.
Used in Neurological Applications:
Calebin-A is used as a potential therapeutic agent for neurological disorders, thanks to its demonstrated neuroprotective effects. Further research is required to explore its full potential in this area.
Used in Antioxidant and Anti-inflammatory Applications:
As a member of the curcuminoid family, Calebin-A is used for its antioxidant and anti-inflammatory properties, which can be beneficial in the prevention and treatment of various diseases and conditions related to oxidative stress and inflammation.
Used in the Food Industry:
Calebin-A, being a natural compound found in turmeric, can be utilized in the food industry as a natural additive for its antioxidant and anti-inflammatory properties, potentially enhancing the health benefits of certain food products.

Check Digit Verification of cas no

The CAS Registry Mumber 1262675-76-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,6,2,6,7 and 5 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1262675-76:
(9*1)+(8*2)+(7*6)+(6*2)+(5*6)+(4*7)+(3*5)+(2*7)+(1*6)=172
172 % 10 = 2
So 1262675-76-2 is a valid CAS Registry Number.

1262675-76-2Relevant academic research and scientific papers

Novel insights into the mode of action of vasorelaxant synthetic polyoxygenated chalcones

Abatuci, Yannick,Faure, Sébastien,Helesbeux, Jean-Jacques,Legeay, Samuel,Tran, Kien

, (2020)

Polyphenols consumption has been associated with a lower risk of cardiovascular diseases (CVDs) notably through nitric oxide (NO)- and estrogen receptor α (ERα)-dependent pathways. Among polyphenolic compounds, chalcones have been suggested to prevent end

Silver-catalyzed double-decarboxylative cross-coupling of α-keto acids with cinnamic acids in water: A strategy for the preparation of chalcones

Zhang, Ning,Yang, Daoshan,Wei, Wei,Yuan, Li,Nie, Fafa,Tian, Laijin,Wang, Hua

, p. 3258 - 3263 (2015/03/30)

A silver-catalyzed double-decarboxylative protocol has been proposed for the construction of chalcone derivatives via cascade coupling of substituted α-keto acids with cinnamic acids under the mild aqueous conditions. The developed method for constructing C-C bonds via double-decarboxylative reactions is efficient, practical, and environmentally benign by using the readily available starting materials. It should provide a promising synthesis candidate for the formation of diverse and useful chalcone derivatives in the fields of synthetic and pharmaceutical chemistry.

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