1262780-80-2Relevant academic research and scientific papers
T-BuOK-mediated reductive addition of P(O)-H compounds to terminal alkynes forming β-arylphosphine oxides
Zhang, Ji-Shu,Zhang, Jian-Qiu,Chen, Tieqiao,Han, Li-Biao
, p. 5462 - 5467 (2017)
A novel and efficient t-BuOK-mediated reductive addition of P(O)-H compounds to terminal alkynes was developed. A variety of β-arylphosphine oxides including the valuable β-heteroarylphosphine oxides were produced in moderate to high yields under mild reaction conditions. This reaction may proceed via a tandem process involving regio-selective double addition and subsequent transfer hydrogenation.
Lanthanum-Catalyzed Regioselective Anti-Markovnikov Hydrophosphinylation of Styrenes
Rina, Yesmin Akter,Schmidt, Joseph A. R.
, p. 4261 - 4270 (2019)
A useful and convenient method for sp3 C-P(O) bond formation via direct regioselective hydrophosphinylation of simple and readily available alkenes using a lanthanum-based N,N-dimethylbenzylamine complex (La(DMBA)3) as a precatalyst is demonstrated. The reaction proceeds with perfect atom economy for a wide range of styrenes with secondary phosphine oxides, giving moderate to excellent yields.
Direct C-OH/P(O)-H dehydration coupling forming phosphine oxides
Chen, Long,Zhu, Yueyue,Chen, Tieqiao,Liu, Long,Zhang, Ji-Shu,Han, Li-Biao
, p. 5090 - 5093 (2018)
A t-BuONa-mediated C-OH/P(O)-H cross dehydration coupling to produce alkylphosphine oxides is developed. This reaction employed readily available alcohols and P(O)-H compounds as the starting materials, providing an efficient alternative method for constructing sp3 C-P bonds. A reasonable reaction path involving dehydration and subsequent regio-selective hydrophosphorylation of the resulting alkenes was proposed.
Hydrophosphinylation of Styrenes Catalysed by Well-Defined s-Block Bimetallics
Borys, Andryj M.,Hevia, Eva,Platten, Andrew W. J.
, (2022/02/01)
Advancing the applications of s-block heterobimetallic complexes in catalysis, we report the use of potassium magnesiate (PMDETA)2K2Mg(CH2SiMe3)4 [PMDETA=N,N,N’,N’,N’’-pentamethyldiethylenetriamine] f
Copper-catalyzed hydrophosphinations of styrenes in water at room temperature
Isley, Nicholas A.,Linstadt, Roscoe T. H.,Slack, Eric D.,Lipshutz, Bruce H.
, p. 13196 - 13200 (2014/11/08)
Copper-catalyzed hydrophosphinations of styrenyl systems in water, at room temperature is herein reported, enabled by our 'designer' surfactant TPGS-750-M. This is an attractive alternative to the more common Pd and Pt catalyzed versions.
Copper(I)-catalyzed hydrophosphination of styrenes
Leyva-Pérez, Antonio,Vidal-Moya, Jose A.,Cabrero-Antonino, Jose R.,Al-Deyab, Salem S.,Al-Resayes, Saud I.,Corma, Avelino
experimental part, p. 362 - 367 (2011/02/17)
Hydrophosphination of styrenes has been accomplished with metal salts for the first time. (CuOTf)2·toluene complex is the catalyst of choice, but CuCl can also be used. "In-situ" EPR and NMR studies suggest Cu(I) as the catalytically active metal species, giving exclusively the anti-Markovnikov product. Phosphine oxides or β-ketophosphine oxides can be prepared in one-pot by oxidation with molecular oxygen.
