1263090-21-6

Basic information

• Product Name: 5-chloro-1-tritylindoline-2,3-dione
• Synonyms: 5-chloro-1-tritylindoline-2,3-dione
• CAS NO: 1263090-21-6
• Molecular Weight: 423.898
• Mol File: 1263090-21-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 5-chloro-1-tritylindoline-2,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-chloro-1-tritylindoline-2,3-dione(1263090-21-6)
• EPA Substance Registry System: 5-chloro-1-tritylindoline-2,3-dione(1263090-21-6)

Safety Data

• Hazardous Substances Data: 1263090-21-6(Hazardous Substances Data)

Upstream product

• 596-43-0 bromo-triphenyl-methane 
• 17630-76-1 5-chloroindole 2,3-dione 
• 76-83-5 trityl chloride 

Downstream Products

• 1263090-31-8 C₄₀H₂₈ClNO₄ 
• 1193314-23-6 cipargamin 

Relevant articles and documents

Carbene-Catalyzed Enantioselective Aromatic N-Nucleophilic Addition of Heteroarenes to Ketones

The aromatic nitrogen atoms of heteroarylaldehydes are activated by carbene catalysts to react with ketone electrophiles. Multi-functionalized cyclic N,O-acetal products are afforded in good to excellent yields and optical purities. Our reaction involves the formation of an unprecedented aza-fulvene-type acylazolium intermediate. A broad range of N-heteroaromatic aldehydes and electron-deficient ketone substrates works effectively in this transformation. Several of the chiral N,O-acetal products afforded through this protocol exhibit excellent antibacterial activities against Ralstonia solanacearum (Rs) and are valuable in the development of novel agrichemicals for plant protection.

Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines: Efficient Synthesis of Cipargamin

Highly enantioselective rhodium-catalyzed addition of arylboroxines to N-unprotected ketimines is realized for the first time by employing chiral BIBOP-type ligands with a Rh loading as low as 1 mol %. A range of chiral α-trifluoromethyl-α,α-diaryl α-tertiary amines or 3-amino-3-aryloxindoles were formed with excellent ee values and yields by employing either WingPhos or PFBO-BIBOP as the ligand. The method has enabled an efficient enantioselective synthesis of cipargamin.

Construction of chiral quaternary carbon through morita-baylis-hillman reaction: An enantioselective approach to 3-substituted 3-hydroxyoxindole derivatives

A new enantioselective approach to obtain a tetrasubstituted chiral center at the C3 position of oxindoles via a catalytic asymmetric Morita-Baylis-Hillman reaction has been demonstrated. This reaction provides 3-substituted 3-hydroxy-2-oxindoles in good