1263218-33-2Relevant academic research and scientific papers
Structural study on solvates of dopamine-based cyclic imide derivatives
Singh, Devendra,Baruah, Jubaraj B.
, p. 768 - 777 (2011)
A structural study on two dopamine-based imide derivatives, namely, 2-(3,4-dihydroxyphenethyl)isoindole-1,3-dione (1) and 2,6-bis-[2-(3,4- dihydroxyphenyl)ethyl]pyrrolo [3,4-f]isoindole-1,3,5,7-tetrone (2), and their solvates was carried out. The compound 1 (Z′ = 2) was crystallized through a melt crystallization process, whereas its two solvates (Z′ = 1 of each), containing one water molecule (1a) and the other containing two quinoline molecules (1b) in their crystal lattices, respectively, were obtained through solution crystallization. The reasons for Z′ = 2 arising from symmetry nonequivalent molecules in the unit cell of 1 is attributed to the nonparallel arrangement of two layers of self-assembled molecules in crystal lattice, where one layer has C-H???π and another layer has C=O???π interactions. Four different solvates of compound 2 (Z′ = 0.5 of each), containing two DMF molecules (2a), two DMSO molecules (2b), two pyridine molecules (2c), and six quinoline molecules (2d), were also obtained through solution crystallization of 2 in respective solvents. Solvate 2d has channels in its structure which are formed by interaction of 2 with quinoline molecules through O-H???N and C-H???π interactions. Additional quinoline molecules reside in these channels of approximately (11 × 12) A dimension. Structural features of all the compounds and their solvates have been studied by single crystal X-ray structures, powder X-ray diffractions (PXRD), thermogravimetric analyses (TGA), and differential scanning calorimetric (DSC) measurements.
