126352-82-7

Basic information

• Product Name: Pyrazolo[1,5-a]pyrimidine-4(5H)-carboxaldehyde, 6,7-dihydro- (9CI)
• Synonyms: Pyrazolo[1,5-a]pyrimidine-4(5H)-carboxaldehyde, 6,7-dihydro- (9CI);6,7-Dihydropyrazolo[1,5-a]pyrimidine-4(5H)-carbaldehyde
• CAS NO: 126352-82-7
• Molecular Formula: C₇H₉N₃O
• Molecular Weight: 151.16586
• Product Categories: ALDEHYDE
• Mol File: 126352-82-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrazolo[1,5-a]pyrimidine-4(5H)-carboxaldehyde, 6,7-dihydro- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazolo[1,5-a]pyrimidine-4(5H)-carboxaldehyde, 6,7-dihydro- (9CI)(126352-82-7)
• EPA Substance Registry System: Pyrazolo[1,5-a]pyrimidine-4(5H)-carboxaldehyde, 6,7-dihydro- (9CI)(126352-82-7)

Safety Data

• Hazardous Substances Data: 126352-82-7(Hazardous Substances Data)

Upstream product

• 64-18-6 formic acid 
• 126352-69-0 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine 
• 144-55-8 sodium hydrogencarbonate 

Downstream Products

• 148777-84-8 3-nitro-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine 

Relevant articles and documents

Studies on 3'-quaternary ammonium cephalosporins - III. Synthesis and antibacterial activity of 3'-(3-aminopyrazolium)cephalosporins

The synthesis and in vitro antibacterial activity of 7β-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido] cephalosporins bearing N-mono or dialkyl and carbamoyl aminopyrazolium, and five- or six-membered rings fused to the 3-aminopyrazolium methyl groups at the 3-position, are described. Aminopyrazolium methyl cephalosporins (23e, f, i), with fused saturated and unsaturated rings were especially effective against Staphylococcus strains compared to 3-amino-2-methylpyrazolium methyl cephalosporin (1). Among the cephalosporins prepared in this work, 7β-[(Z)-2-(2-aminothiazol-4-yl)-2-methoxyimino acetamidol-3-(4,5,6,7-tetrahydro-1-pyrazolo[1,5-a] pyrimidinio)methyl-3-cephem-4-carboxylate (23f) showed a good balance of antibacterial activity against both Gram-positive bacteria including Staphylococcus aureus and Gram-negative bacteria including P. aeruginosa. An imidazopyrazolium group at the 3-position in, for example, cephalosporin (23i) was particularly effective for improving antibacterial activity against MRSA.