1265153-65-8Relevant articles and documents
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: Effect of core substitutions and salt formation
Reid, Carolyn S.,Patrick, Donald A.,He, Shanshan,Fotie, Jean,Premalatha, Kokku,Tidwell, Richard R.,Wang, Michael Zhuo,Liu, Qiang,Gershkovich, Pavel,Wasan, Kishor M.,Wenzler, Tanja,Brun, Reto,Werbovetz, Karl A.
, p. 513 - 523 (2011/03/17)
Analogs of the trypanocidal lead compound 1-benzyl-1,2-dihydro-2,2,4- trimethylquinolin-6-yl acetate were prepared to extend the structure-activity relationship in this series of molecules, improve the in vivo antitrypanosomal activity of the lead, and de