1265632-32-3Relevant academic research and scientific papers
Cyclopropenium-activated cyclodehydration of diols
Kelly, Brendan D.,Lambert, Tristan H.
, p. 740 - 743 (2011)
The dehydrative cyclization of diols to cyclic ethers via cyclopropenium activation is described. Using 2,3-diphenylcyclopropene and methanesulfonic anhydride, a series of 1,4-and 1,5-diols are rapidly cyclized to furnish tetrahydrofurans and tetrahydropyrans in high yield. Eleven total substrates are shown, including a gram scale cyclization of a diterpene derivative.
