1267158-57-5

Basic information

• Product Name: 1-(3-methoxyphenyl)-2-(pyrrolidin-1-yl) ethane-1,2-dione
• Synonyms: 1-(3-methoxyphenyl)-2-(pyrrolidin-1-yl) ethane-1,2-dione
• CAS NO: 1267158-57-5
• Molecular Weight: 233.267
• Mol File: 1267158-57-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-(3-methoxyphenyl)-2-(pyrrolidin-1-yl) ethane-1,2-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-methoxyphenyl)-2-(pyrrolidin-1-yl) ethane-1,2-dione(1267158-57-5)
• EPA Substance Registry System: 1-(3-methoxyphenyl)-2-(pyrrolidin-1-yl) ethane-1,2-dione(1267158-57-5)

Safety Data

• Hazardous Substances Data: 1267158-57-5(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 766-85-8 3-methoxy-1-iodobenzene 
• 201230-82-2 carbon monoxide 
• 768-70-7 1-ethynyl-3-methoxybenzene 
• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 32025-65-3 3-methoxyphenylglyoxal 
• 1442748-91-5 C₁₁H₁₆O₄ 
• 87428-52-2 2-hydroxy-3'-methoxyacetophenone 

Relevant articles and documents

Visible-Light Mediated Photooxidative Synthesis of α-Keto Amides

Photocatalytic amidation of α-keto aldehydes is herein investigated. This transformation was achieved using rose bengal as photocatalyst at room temperature under ambient air and under irradiation of a 20 W white LED bulb. The method is mild, efficient an

Direct Aerobic Oxidative Reactions of 2-Hydroxyacetophenones

Valuable and direct aerobic oxidation reactions of 2-hydroxyacetophenones were explored. The concept was based on the in situ treatment of small quantities of aerobically formed α-keto aldehydes that drove the reactions to the corresponding products. This new strategy was applied for a variety of oxidative reactions of 2-hydroxyacetophenones, and valuable products such as phthalides, quinoxalines, and α-keto amides were obtained in good to high yields.

Metal-free oxidative amidation of 2-oxoaldehydes: A facile access to α-ketoamides

A novel and efficient method for the synthesis of α-ketoamides, employing a dimethyl sulfoxide (DMSO)-promoted oxidative amidation reaction between 2-oxoaldehydes and amines under metal-free conditions is presented. Furthermore, mechanistic studies supported an iminium ion-based intermediate as a central feature of reaction wherein C1-oxygen atom of α-ketoamides is finally derived from DMSO.